Rapid Methods for detection of Veterinary Drug residues in Meat

Shankar, Shankar; BP, BP; Prabhu, Manjunatha; BH, BH; Chandan, Chandan; S, S; Ranjith, Ranjith; Shivakumar, D; V, V

doi:10.5455/vetworld.2010.241-246

Cited by 38 publications

(47 citation statements)

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“…[11] Antibiotics are used in the treatment and prevention of these diseases as well as a growth promoting agent. [12] The presence of antibiotic residues in poultry meat has received colossal worldwide attention from public health agencies. This is owing to the importance and significance of antibiotic residues on public health.…”

Section: Discussionmentioning

confidence: 99%

Determination of Enrofloxacin Residues in Commercial Broilers Using High Performance Liquid Chromatography

Aslam

Kousar

Javed

et al. 2016

International Journal of Food Properties

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The broad-spectrum antibacterial drugs are widely used in food producing animals. Suspected residues of these drugs in meat may have ill effects upon human health. The aim of the present study was to determine the enrofloxacin (ENRO) residues in broiler's meat and liver samples.Detection of ENRO residues in meat (n=75) and liver (n=75) samples was performed by high performance liquid chromatography with UV detector set at 268 nm using C 18 column. Overall mean residual concentrations of ENRO in meat and liver samples were 208±55 and 527±84 µg/kg respectively. This study revealed that 52% (39) meat and 78.7% (59) liver samples were positive for ENRO, out of these 58.3% (21) meat and 71.2% (42) liver samples were having residual concentration above the maximum residual limits. So it can be concluded that the usage Downloaded by [New York University] at 23:13 30 May 2015A c c e p t e d M a n u s c r i p t 2 of this contaminated meat may cause resistance in consumers and seems to be a public health threat.

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Section: Discussionmentioning

confidence: 99%

Determination of Enrofloxacin Residues in Commercial Broilers Using High Performance Liquid Chromatography

Aslam

Kousar

Javed

et al. 2016

International Journal of Food Properties

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“…Chronic and acute human exposure to veterinary drugs through ingestion of their residues in poultry products are associated with the development of allergic reaction in hypersensitive individuals (Shankar et al 2010), the alteration of human intestinal micro-flora (Shankar et al 2010) as well as induction and generation of resistant strains of human pathogenic bacteria (Kabir et al 2004). The presence of veterinary drug residues in poultry above tolerance levels constitutes a healthcare problem and presents public health concerns (Verbeke and Viaene 2000;Leibler et al 2004).…”

Section: Introductionmentioning

confidence: 96%

Estimated dietary exposure to veterinary residues in chicken and eggs

et al. 2015

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Background: Chicken tissues and eggs were analyzed for residues of eight veterinary drugs including albendazole, piperazine, tiamulin, chloramphenicol, levamisole, sulphathiazole, sulphamethoxazole and oxytetracyclineoxytetracycline. Results: Mean residue concentrations of all drugs varied by tissue and ranged from 0.004 μg/kg for tiamulin in eggs to 8.6 μg/kg for chloramphenicol in liver. Total residues of all drugs in the liver generally exceeded that of the kidney, muscles and eggs by at least a two-fold difference. The general order of decreasing total drug residue levels is liver > kidney > muscle > eggs. The exposure due to albendazole and sulphamethoxazole in liver were 2-and 7-folds higher than their recommended average daily intake. Exposure due to piperazine, sulphamethoxazole, levamisole and tiamulin were, however, lower than their respective recommended limits. Conclusion: Dietary exposure assessments of all drugs based on quantitated residue levels are within the Joint FAO/ WHO Expert Committee on Food Additives safe regulatory exposure limits. This study informs the public about veterinary drug residues in poultry and helps address policy and regulatory changes in the use of veterinary drugs in poultry.

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“…The methodologies and full procedure for confirmatory analysis require trained personnel with high expertise and they are costly in time, chemicals and equipments 21 . Identification is easier for a limited number of target analytes which are obtained with screening methods.…”

Section: Discussionmentioning

confidence: 99%

Use of Elisa for Preliminary Screening of 19 Nortestosterone Anabolic Steroid in Cattle Meat in Republic of Macedonia

Uzunov¹,

Hajrulai-Musliu²,

Dimitrievska-Stojkovic³

et al. 2013

Kafkas Univ Vet Fak Derg

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SummaryIn recent years, hormones and hormone like substances have been recently used in livestock production to obtain a high yield performance in a shorter period of time. These anabolic agents are used to increase the weight gain, to improve the food efficiency, storing protein and to decrease fatness. However, depending on the use of anabolic agent in animal feed, anabolic residues that may occur in meat and meat products present risks to human health. The aim of this study was to detect the levels of 19 nortestosterone residues in the market cattle meat in R. Macedonia. In this study, a total of 86 samples were obtained from different markets and used as a test material. 19 nortestosterone residues were analyzed with ELISA method. The average experimental level of 19 nortestosterone in cattle meat was 375.20 ppt. The recovery was between 79.54% and 114.39%, a working range between 50 to 3.000 ppt. The regression equation of the final inhibition curve was: y = -0.1453 x +1.4057, R 2 = 0.9972. The levels of 19 nortestosterone residues were below the international allowable levels set by the Macedonian Residue Control Plan and the European Union. According to the results of our study on this anabolic steroid, the obtained 86 cattle meat samples are safe for human consumption. However, it is still necessary to monitor this chemical as a food quality control measure.

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Rapid Methods for detection of Veterinary Drug residues in Meat

Cited by 38 publications

References 0 publications

Determination of Enrofloxacin Residues in Commercial Broilers Using High Performance Liquid Chromatography

Determination of Enrofloxacin Residues in Commercial Broilers Using High Performance Liquid Chromatography

Estimated dietary exposure to veterinary residues in chicken and eggs

Use of Elisa for Preliminary Screening of 19 Nortestosterone Anabolic Steroid in Cattle Meat in Republic of Macedonia

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