“…A mass spectroscopic method employing hydrophilic interaction liquid chromatography (HILIC-MS/MS) improved the detection sensitivity of levosulpiride to 1 ng/mL, but resulted in a longer runtime, of 7 min [20]. A recently developed LC-MS/MS method, boasting short analysis times and analyte elution within 1 min, has yet to be validated with regard to percent recovery, specificity, and stability [21]. Thus, there is still a continuing need for a specific, simple, rapid, and well-validated method that is suitable for high-throughput bioanalytical applications.…”