Rapid recognition and determination of tryptophan by carbon nanotubes and molecularly imprinted polymer-modified glassy carbon electrode

Wu, Yiyong; Deng, Peihong; Tian, Yaling; Ding, Ziyu; Li, Guangli; Li, Jun; Zuberi, Zavuga; He, Quanguo

doi:10.1016/j.bioelechem.2019.107393

Cited by 176 publications

(72 citation statements)

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“…Since the experimental discovery of monolayer by Novoselov and Geim [21], GR has attracted much attention due to its unique properties. The applications of GR or GR-based nanocomposites in high sensitivity and high selectivity electrochemical sensors have been widely reported, such as dopamine [22][23][24], 4-nitrophenol [25], rutin [26], tryptophan [27], sunset yellow [28], quinoline yellow [29], glucose [30], serotonin [31], acetaminophen [32], 4-aminophenol [33] and methyl parathion [34] sensors. Although GR has significant electrocatalytic and sensing properties, it has been reported that in most solvents, due to van der Waals interaction and strong π-π stacking, GR nanosheets are clustered together in a short time [35].…”

Section: Introductionmentioning

confidence: 99%

Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE

Liu

Feng

et al. 2020

Nanomaterials

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In this paper, an electrochemical method for the measurement of tryptophan (Trp) was developed based on a glassy carbon electrode modified with polyvinylpyrrolidonefunctionalized graphene (PVP-GR)/glassy carbon electrode (GCE). In 0.1 M phosphate buffer solution (PBS, pH = 2.2), compared with bare GCE, PVP/GCE, and GR/GCE, the oxidation peak current of Trp increased dramatically at PVP-GR/GCE. The oxidation mechanism of Trp on the PVP-GR/GCE was discussed and the experimental conditions were optimized. Under the best experimental conditions, the oxidation peak current of Trp was proportional to its concentration in the range of 0.06 µM–10.0 µM and 10.0–100.0 µM, and the limit of detection (LOD) was 0.01 µM (S/N = 3). The target modified electrode with excellent repeatability, stability and selectivity, was successfully applied to detectTrp in drugs and biological samples.

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Section: Introductionmentioning

confidence: 99%

Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE

Liu

Feng

et al. 2020

Nanomaterials

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“…For example, graphene has been composited with MIPs to quantify dopamine (DA) in human serum and urine (105). Similarly, tryptophan has been measured in human serum with MIPs composited with carbon nanotubes (106). Lastly, cancer detection has been evaluated through a comparison of MIPbased optical and ECM biosensors (107).…”

Section: Biosensor Applicationsmentioning

confidence: 99%

“…Multi-walled carbon nanotubes (MWCNTs) have been layered onto an ECM sensor electrode with inexpensive, biocompatible chitosan MIPs for determination of tryptophan (106) (Fig. 2d).…”

Section: Carbon Nanomaterials (Cnms)mentioning

confidence: 99%

Point-of-Care Diagnostics: Molecularly Imprinted Polymers and Nanomaterials for Enhanced Biosensor Selectivity and Transduction

Denmark

Mohapatra

2020

The EuroBiotech Journal

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Significant healthcare disparities resulting from personal wealth, circumstances of birth, education level, and more are internationally prevalent. As such, advances in biomedical science overwhelmingly benefit a minority of the global population. Point-of-Care Testing (POCT) can contribute to societal equilibrium by making medical diagnostics affordable, convenient, and fast. Unfortunately, conventional POCT appears stagnant in terms of achieving significant advances. This is attributed to the high cost and instability associated with conventional biorecognition: primarily antibodies, but nucleic acids, cells, enzymes, and aptamers have also been used. Instead, state-of-the-art biosensor researchers are increasingly leveraging molecularly imprinted polymers (MIPs) for their high selectivity, excellent stability, and amenability to a variety of physical and chemical manipulations. Besides the elimination of conventional bioreceptors, the incorporation of nanomaterials has further improved the sensitivity of biosensors. Herein, modern nanobiosensors employing MIPs for selectivity and nanomaterials for improved transduction are systematically reviewed. First, a brief synopsis of fabrication and wide-spread challenges with selectivity demonstration are presented. Afterward, the discussion turns to an analysis of relevant case studies published in the last five years. The analysis is given through two lenses: MIP-based biosensors employing specific nanomaterials and those adopting particular transduction strategies. Finally, conclusions are presented along with a look to the future through recommendations for advancing the field. It is hoped that this work will accelerate successful efforts in the field, orient new researchers, and contribute to equitable health care for all.

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“…Selectivity and stability of the disposable electrode IFV A (H1N1) and hepatitis E virus (HEV), various solution containing impurity, metal ions were used for the selectivity test of the Ab-N,S-GQD@AuNP-PAni/CSR electrode. In addition, solutions containing foreign substances was used to evaluate the practicability of the sensor in accordance with the cited references [40][41][42]. To con rm the stability, the disposable electrodes were preserved at 4°C for 60 d, testing the performance of the electrodes every week.…”

Section: Western Blot Analysis Of Wssv-vp28mentioning

confidence: 99%

Electrochemical detection of white spot syndrome virus with a silicone rubber disposable electrode composed of graphene quantum dots and gold nanoparticle-embedded polyaniline nanowires

Takemura

Satoh²,

Boonyakida

et al. 2020

Preprint

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Background: With the enormous increment of globalization and global warming, it is expected that the number of newly evolved infectious diseases will continue to increase. To prevent damage due to these infections, the development of a diagnostic method for detecting a virus with high sensitivity in a short time is highly desired. In this study, we have developed a high-sensitivity and high-accuracy disposable electrode and evaluated it for several target viruses. Results: Conductive silicon rubber (CSR) was used to fabricate a disposable sensing matrix composed of nitrogen and sulfur-codoped graphene quantum dots (N,S-GQDs) and a gold-polyaniline nanocomposite (AuNP-PAni). A specific anti-white spot syndrome virus (WSSV) antibody was conjugated to the surface of this nanocomposite, which wassuccessfully applied for the detection of WSSV over a wide linear range of 1.45 × 10 2 to 1.45 × 10⁵ DNA copies/ml, with a detection limit as low as 48.4 DNA copies/ml. Conclusion: The engineered sensor electrode can retain the detection activity for up to 5 weeks, a vital long-term stability requirement for disposable sensing applications. This is the first demonstration of the detection of WSSV by ananofabricated sensing electrode with high sensitivity, selectivity, and stability, providing a potential diagnostic tool to monitor WSSV in the aquaculture industry.

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Rapid recognition and determination of tryptophan by carbon nanotubes and molecularly imprinted polymer-modified glassy carbon electrode

Cited by 176 publications

References 50 publications

Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE

Sensitive Voltammetric Sensor for Tryptophan Detection by Using Polyvinylpyrrolidone Functionalized Graphene/GCE

Point-of-Care Diagnostics: Molecularly Imprinted Polymers and Nanomaterials for Enhanced Biosensor Selectivity and Transduction

Electrochemical detection of white spot syndrome virus with a silicone rubber disposable electrode composed of graphene quantum dots and gold nanoparticle-embedded polyaniline nanowires

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