Rapid Syphilis Testing Is Cost-Effective Even in Low-Prevalence Settings: The CISNE-PERU Experience

Mallma, Patricia; García, Patricia J.; Cárcamo, César; Torres-Rueda, Sergio; Peeling, Rosanna W.; Mabey, David; Terris‐Prestholt, Fern

doi:10.1371/journal.pone.0149568

Cited by 18 publications

(36 citation statements)

References 18 publications

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“…In some of these studies, such as one in Delhi [45], POCTT still had good performances (sensitivity -75 %, specificity -100 %, positive predictive value -100 %, negative predictive value -99.45 %), even when in samples from lowprevalence (2 %) populations of pregnant women. The same was found by Malla et al (2016) [46] in low-prevalence settings in Peru.…”

Section: Poc Tests' Performancesupporting

confidence: 86%

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The role of Point-of-Care testing in the diagnosis of syphilis

Castro¹,

Pereira²

2017

Point-of-Care Diagnostics - New Progresses and Perspectives

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Section: Poc Tests' Performancesupporting

confidence: 86%

“…Nowadays, antenatal screening and treatment of maternal syphilis are cost-effective health interventions [62], even under low prevalence of infection of 1 and 2 %, as shown by Kashiap et al (2015) [45] and Mallma et al (2015) [46], especially when using POCTT.…”

Section: Impact Of Tests' Introductionmentioning

confidence: 99%

The role of Point-of-Care testing in the diagnosis of syphilis

Castro¹,

Pereira²

2017

Point-of-Care Diagnostics - New Progresses and Perspectives

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“…The difference in availability between tests for HIV and those for syphilis and anaemia reflects the high international priority and substantial financial support given to vertical HIV programmes resulting in parallel procurement and supervisory systems developed to ensure their accessibility and use [ 43 , 44 ]. Syphilis and haemoglobin screening, despite the strong evidence for their clinical effectiveness [ 45 – 47 ], lack such donor advocacy and prioritization and suffer inadequate coverage [ 43 , 44 ].…”

Section: Introductionmentioning

confidence: 99%

Integrated point-of-care testing (POCT) of HIV, syphilis, malaria and anaemia in antenatal clinics in western Kenya: A longitudinal implementation study

et al. 2018

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BackgroundIn sub-Saharan Africa, HIV, syphilis, malaria and anaemia are leading preventable causes of adverse pregnancy outcomes. In Kenya, policy states women should be tested for all four conditions (malaria only if febrile) at first antenatal care (ANC) visit. In practice, while HIV screening is conducted, coverage of screening for the others is suboptimal and early pregnancy management of illnesses is compromised. This is particularly evident at rural dispensaries that lack laboratories and have parallel programmes for HIV, reproductive health and malaria, resulting in fractured and inadequate care for women.MethodsA longitudinal eight-month implementation study integrating point-of-care diagnostic tests for the four conditions into routine ANC was conducted in seven purposively selected dispensaries in western Kenya. Testing proficiency of healthcare workers was observed at initial training and at three monthly intervals thereafter. Adoption of testing was compared using ANC register data 8.5 months before and eight months during the intervention. Fidelity to clinical management guidelines was determined by client exit interviews with success defined as ≥90% adherence.FindingsFor first ANC visits at baseline (n = 529), testing rates were unavailable for malaria, low for syphilis (4.3%) and anaemia (27.8%), and near universal for HIV (99%). During intervention, over 95% of first attendees (n = 586) completed four tests and of those tested positive, 70.6% received penicillin or erythromycin for syphilis, 65.5% and 48.3% received cotrimoxazole and antiretrovirals respectively for HIV, and 76.4% received artemether/lumefantrine, quinine or dihydroartemisinin–piperaquine correctly for malaria. Iron and folic supplements were given to nearly 90% of women but often at incorrect doses.ConclusionsIntegrating point-of-care testing into ANC at dispensaries with established HIV testing programmes resulted in a significant increase in testing rates, without disturbing HIV testing rates. While more cases were detected and treated, treatment fidelity still requires strengthening and an integrated monitoring and evaluation system needs to be established.

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“…Fatores associados à transmissão vertical e maior incidência estão relacionados, também, a menor escolaridade materna, cor da pele, menor proporção de consultas e realização de exames no período gravídico (DOMINGUES & LEAL, 2016;VALLEJO & CIFUENTES, 2015). A prevalência e o perfil epidemiológico da sífilis apareceram com mais frequência, assim como a sua forma de transmissão, os métodos de diagnósticos mais eficazes e o tratamento (PINTO, 2016;LIU, 2016;TAYLOR, 2016;MALLMA, 2016;MUTAGOMA, 2016;PARK, 2016;ALMEIDA, 2015;CUNHA, 2015;DOMINGUES, 2014;SERAFIM, 2014;SMIT, 2013;LI, 2013;JAFARI, 2013;MIRANDA, 2012;CAVALCANTE, 2012;GALATOIRE, 2012;HOLANDA, 2011;DIÉZ, 2011;GONÇALVES, 2011;CARVALHO, 2009;ISAM, 2009;SANTOS, 2009;TAYRA, 2007;CONDE-CONZÁLEZ, 2007).…”

Section: Resultsunclassified

Pandemias: Impactos na sociedade

2020

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Introduction: Academic training is built by the traditional classroom teaching model and in this context, universities at a global level, needing to shape the new reality of social isolation, transferred their classroom classes to remote teaching, removing students from their activities classroom curricula, and consequently, causing a significant emotional impact to the student. Objectives: To identify the impacts on teaching-learning of nursing students in the face of the pandemic of covid-19; analyze remote teaching as contribution strategies for nursing education; describe the role of nursing students without their teachinglearning process. Methodology: This is a literature review, with a qualitative approach and descriptive character. After the reflective reading of the 14 articles, three categories emerged. Results and Discussion: Due to the impacts of the pandemic triggering the closure of teaching units, a change was proposed in the realization of face-to-face classes by online classes, so that students could use any technological device to attend classes. Conclusion: There is a need to adhere to new pedagogical methodologies, analyze the scenario, plan and implement elements in an attempt to conduct higher education in the pandemic period. In addition, promoting initiatives offering opportunities for teachers and students as protagonists in the search for knowledge.

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Rapid Syphilis Testing Is Cost-Effective Even in Low-Prevalence Settings: The CISNE-PERU Experience

Cited by 18 publications

References 18 publications

The role of Point-of-Care testing in the diagnosis of syphilis

The role of Point-of-Care testing in the diagnosis of syphilis

Integrated point-of-care testing (POCT) of HIV, syphilis, malaria and anaemia in antenatal clinics in western Kenya: A longitudinal implementation study

Pandemias: Impactos na sociedade

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