Rapid testing of red blood cells, white blood cells and platelets in intensive care patients using the HemoScreen™ point-of-care analyzer

Larsson, Anders; Smékal, David; Lipcsey, Miklós

doi:10.1080/09537104.2018.1557619

Cited by 16 publications

(12 citation statements)

References 22 publications

(31 reference statements)

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“…Over the entire measuring range, we found that the HemoScreen correlated very well for the routine samples in all five parameters to those generated by the Sysmex XN (Figures ). As seen by Larsson et al, 29 the HemoScreen, at low PLT counts, tend to slightly underestimate the counts compare with the Sysmex instrument (Figures 2B and 4B); however, this is of no clinical importance.…”

Section: Discussionmentioning

confidence: 57%

The HemoScreen hematology point‐of‐care device is suitable for rapid evaluation of acute leukemia patients

Kur

Thøgersen

Kjeldsen

et al. 2020

Int J Lab Hematology

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Background Hematological patients, receiving intensive chemotherapy (predominantly acute leukemia patients), have repeated postchemotherapy periods with severe bone marrow suppression. As a result, these patients require regular monitoring of the complete blood counts (CBC) for optimal patient care. To reduce the strain on the patient, there is a need for a point‐of‐care (POC) hematology device that provides rapid and reliable results both in general and in cytopenic samples and is suitable for outpatient clinics. We evaluated the HemoScreen device for the most used CBC parameter both overall and at the lower range. Methods The HemoScreen was compared with the Sysmex XN‐9000 in 206 routine venous samples and 79 capillary bedside samples focusing on white blood cells (WBC), absolute neutrophil count (ANC), red blood cells (RBC), PLT and HGB. Results The HemoScreen was less precise compared to the acceptance criteria set for larger and more advanced hematology instrument with a CV% 3.0‐3.7 for WBCs, 3.6‐8.4 for ANCs, 1.1‐1.5 for RBCs, 2.5‐4.4 for PLTs, and 1.7‐2.3 for HGB. Correlation coefficient for all five parameters for the entire range was r >.95 and r >.90 at lower range for venous and capillary samples. Bias limits were within the CTCAE acceptance limits. Conclusions The HemoScreen provides rapid and accurate test results, for evaluation of WBC, PLT, and HGB, as well as at low concentrations for guiding transfusions and postchemotherapy treatment. The device is easy to operate and can measure both venous and capillary samples. Therefore, the HemoScreen is well suited for smaller outpatient clinics and potentially home use.

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Section: Discussionmentioning

confidence: 57%

The HemoScreen hematology point‐of‐care device is suitable for rapid evaluation of acute leukemia patients

Kur

Thøgersen

Kjeldsen

et al. 2020

Int J Lab Hematology

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“…Las correlaciones de Deming entre el HemoScreen y el analizador de Sysmex XN: Leucocitos (Leucocitos HemoScreen™ = 1.061* Lecucoitos Sysmex -0.644; r = 0.995), eritrocitos (Eritrocitos HemoScreen™ = 0.998* Eritrocitos ysmex + 0.049; r = 0.993) y plaquetas (Plaquetas HemoScreen™ = 1.087* Plaquetas Sysmex -14.80; r = 0.994). El dispositivo HemoScreen™ produce resultados rápidos y exactos para evaluar las necesidades de transfusión de glóbulos rojos y de plaquetas 33 .…”

Section: Analizador Hematológico Automatizadounclassified

¿La medición de hemoglobina es más costo-efectiva que el uso del hemograma automatizado?

Vásquez‐Velásquez¹,

Aguilar-Cruces²,

López-Cuba³

et al. 2019

Investigación Materno Perinatal

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De acuerdo con la Organización Mundial de la Salud (OMS), hay 802 millones de personas entre niños en edad pre-escolar, y mujeres en edad reproductiva que son diagnosticadas de anemia. Estas cifras muestran un panorama poco alentador para los gobiernos, puesto que vemos el gran énfasis en los programas de suplementación de hierro, con distribución a nivel nacional. Sin embargo, los valores reportados en las encuestas y las grandes bases de datos que se utilizan para la elaboración de estadísticas nacionales se basa en la medición de la hemoglobina mediante el equipo HemoCue®, que presenta variantes entre los equipos y que reportan valores que no permiten determinar la causa de la anemia, basando la intervención solo en la suplementación de hierro, cuando a nivel mundial se ha determinado que solo el 50% de casos de anemia se deben a deficiencia de hierro, 42% a causas inflamatorias y 8% a otras causas. En el reporte de 2016, la OMS recomendó como primera prioridad la evaluación del hemograma completo para definir anemia, y cuando no exista esta facilidad usar la medición de la hemoglobina. En la presente revisión narrativa se hará un análisis de cada metodología y la utilidad tanto para la práctica clínica como para el uso poblacional en el diagnóstico de la anemia gestacional.

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“…Currently, there has been the use of point-of-care hemoglobin (POC-Hb) for hemoglobin measurement. Many studies have reported the clinical use of POC-Hb in various settings, including blood donation [6][7][8] and anemia screening [7], hemoglobin monitoring during cardiac operation [9], and hemoglobin measurement in intensive care unit patients [10,11]. Hemoglobin is a protein in red blood cells and functions in oxygen delivery to the tissues.…”

Section: Introductionmentioning

confidence: 99%

Comparison between blood hemoglobin concentration determined by point-of-care device and complete blood count in adult patients with dengue

et al. 2021

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Background Hematocrit measurement has been an indispensable tool for monitoring plasma leakage and bleeding in dengue patients. However, hematocrit measurement by automated methods is hampered by frequent venipunctures. Utility of point-of-care hemoglobin (POC-Hb) test for monitoring dengue patients has not been established. We evaluated the relationship between hemoglobin measured by POC-Hb testing and hematocrit measured by the automated method in adult dengue patients. Methodology and principal findings Adult dengue patients were recruited at two university hospitals in Thailand from October 2019 to December 2020. POC-Hb test was performed using capillary blood simultaneously with venipuncture to obtain whole blood for an automated complete blood count (CBC) analysis. The correlation of hemoglobin and hematocrit measurement was evaluated. A total of 44 dengue patients were enrolled. Twenty-nine patients (65.9%) were female, with a median age of 31 years (interquartile range 22–41). Of the enrolled patients, 30 (68.2%), 11 (25.0%), and 3 (6.8%) were classified as dengue without warning signs, with warning signs, and severe dengue, respectively. Seven patients (15.9%) had hemoconcentration, and five patients (11.3%) had bleeding. A total of 216 pairs of POC-Hb and CBC were evaluated. A significant positive correlation was observed between hemoglobin measured by POC-Hb testing and hematocrit measured by an automated CBC (r = 0.869, p <0.001). Bland-Altman analysis between hemoglobin measured by POC-Hb testing and an automated CBC showed a bias of -0.43 (95% limit of agreement of -1.81 and 0.95). Using the cutoff of POC-Hb ≥20% as a criteria for hemoconcentration, the sensitivity and specificity of hemoconcentration detected by POC-Hb device were 71.4% and 100.0%, respectively. Conclusions Hemoglobin measurement by POC-Hb testing has a strong correlation with hematocrit in adult patients with dengue fever. However, the sensitivity in detecting hemoconcentration is fair. The adjunct use of capillary POC-Hb testing can decrease the frequency of venipuncture. Further study in children is encouraged.

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Rapid testing of red blood cells, white blood cells and platelets in intensive care patients using the HemoScreen™ point-of-care analyzer

Cited by 16 publications

References 22 publications

The HemoScreen hematology point‐of‐care device is suitable for rapid evaluation of acute leukemia patients

The HemoScreen hematology point‐of‐care device is suitable for rapid evaluation of acute leukemia patients

¿La medición de hemoglobina es más costo-efectiva que el uso del hemograma automatizado?

Comparison between blood hemoglobin concentration determined by point-of-care device and complete blood count in adult patients with dengue

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