Rapid Wound Healing In African Catfish, Clarias Gariepinus, Fed Diets Supplemented With Ascorbic Acid

Abstract

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IL-12/IFN-γ axis drives skin wound healing via innate defense mechanisms against bacterial invasion in teleost fish

“…β-glucan, a pathogenassociated molecular pattern molecule, promotes wound repair and induces cytokine expression in common carp [10]. In addition, vitamin C [11] and plant extracts from walnut leaves and onion bulbs [12] are suggested to enhance wound healing in African cat sh. To date, despite the investigations of immune regulatory compounds that associated with infection-mediated wound repair, little is known on the intrinsic immune mechanisms of teleost skin to ght against pathogen invasion and promote wound repairment, which may also shed a light on the paradigm of comparative immunology between lower vertebrates and mammals.…”