Rare earth activated ZnO nanoparticles as biomarkers

Wolska, E.; Kaszewski, Jarosław; Kiełbik, Paula; Grzyb, Joanna; Godlewski, M.

doi:10.1016/j.optmat.2013.12.032

Cited by 50 publications

(29 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…5), the NP-related red fluorescence is very dim. This could be explained by the low NP content in kidney cells, similar to previous observations (5,12).…”

Section: Resultssupporting

confidence: 89%

“…In the field of biomedicine, one of the most researched applications are drug delivery systems (DDS) (7,8). Many NPs exhibit properties advantageous for DDS, such as the ease of modification, low toxicity, ability to penetrate physiological barriers, favourable biodistribution, biocompatibility and biodegradability (3,5,(9)(10)(11)(12)(13)(14)(15). Furthermore, NPs may also protect a drug from degradation and increase its biological stability, bioavailability and retention time.…”

Section: Praca Oryginalnamentioning

confidence: 99%

“…Marek Godlewski's team from the Institute of Physics, Polish Academy of Sciences (IP PAS), have developed NPs based on wide band-gap semiconductor metal oxides doped with rare earth metal ions to activate their fluorescence (3,5,(11)(12)(13). These NPs, in addition to their strong fluorescence, exhibit many properties important for DDS.…”

Section: Praca Oryginalnamentioning

confidence: 99%

“…Their surface can be easily modified because it is terminated by hydroxide groups. They exhibited low toxicity (2,5), could penetrate physiological barriers, including intestinal and blood-brain barrier and were widely distributed within the body (3,5,(11)(12)(13). In addition, these NPs were either biocompatible or biodegradable (5).…”

Section: Praca Oryginalnamentioning

confidence: 99%

See 3 more Smart Citations

Wide band-gap oxide nanoparticles as potential drug carriers

Lipinski

Kaszewski

Gajewski

et al. 2017

Medycyna Weterynaryjna

View full text Add to dashboard Cite

SummaryRecent decades have brought rapid development in the field of nanotechnology, which has led to applications of nanoparticles in many industries. Unique properties of nanoparticles and their biocompatibility increase their potential as drug carriers in drug-delivery systems. Prof. Marek Godlewski's team from the Institute of Physics PAS has developed wide band-gap metal oxide nanoparticles doped with rare-earth metals for applications as fluorescent markers. The potential of those nanoparticles to cross the closed gut barrier after alimentary application has prompted their use in drug delivery systems. In this study, we show that after conjugation with a model bioactive substance, lectin (Phaseolus vulgaris), these nanoparticles retained their advantageous properties and, following oral administration (10 mg/ml in RO, 0.3 ml/mouse), entered a variety of organs in the mouse model. Internal organs collected at key time points were analysed under a scanning cytometer and a confocal microscope. The results show that the conjugation reduced, but did not completely abolish, the capacity of nanoparticles to penetrate physiological barriers (intestinal, blood-brain barrier) in the organism.

show abstract

“…5), the NP-related red fluorescence is very dim. This could be explained by the low NP content in kidney cells, similar to previous observations (5,12).…”

Section: Resultssupporting

confidence: 89%

Section: Praca Oryginalnamentioning

confidence: 99%

Section: Praca Oryginalnamentioning

confidence: 99%

Section: Praca Oryginalnamentioning

confidence: 99%

See 2 more Smart Citations

Wide band-gap oxide nanoparticles as potential drug carriers

Lipinski

Kaszewski

Gajewski

et al. 2017

Medycyna Weterynaryjna

View full text Add to dashboard Cite

show abstract

“…It is also known that synthesis conditions have a significant effect on the morphology and optical properties of the produced materials [12,13]. Optical, topographical and structural properties of Eu doped ZnO nanopowders obtained by hydrothermal method have been investigated earlier [14]. However, there is a lack of detailed studies on the effect of synthesis pressure on these features.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Synthesis Pressure on Properties of Eu-Doped ZnO Nanopowders Prepared by Microwave Hydrothermal Method

et al. 2016

Self Cite

View full text Add to dashboard Cite

In the current research, europium doped ZnO nanopowders prepared by a microwave hydrothermal method are investigated. The effects of synthesis pressure on the morphologies, crystal structures, and optical properties of Eu-doped ZnO were analyzed by scanning electron microscopy, X-ray diffraction, cathodo-and photoluminescence. From our investigations it can be concluded that the synthesis pressure strongly influences the surface morphology. With the increase of the synthesis pressure from 2 MPa to 10 MPa significant changes can be observed. An increase of the mean crystallites sizes and change of the intensity ratio between the near band edge and defect related deep level emission band of ZnO were observed.

show abstract

Improving upconversion luminescence efficiency in Er3+-doped NaYF4 nanocrystals by two-color laser field

Yao

Zheng

et al. 2016

J Mater Sci

View full text Add to dashboard Cite

Rare earth activated ZnO nanoparticles as biomarkers

Cited by 50 publications

References 18 publications

Wide band-gap oxide nanoparticles as potential drug carriers

Wide band-gap oxide nanoparticles as potential drug carriers

The Effect of Synthesis Pressure on Properties of Eu-Doped ZnO Nanopowders Prepared by Microwave Hydrothermal Method

Improving upconversion luminescence efficiency in Er3+-doped NaYF4 nanocrystals by two-color laser field

Contact Info

Product

Resources

About