2015
DOI: 10.4269/ajtmh.15-0239
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Rare Presentation of Disseminated Histoplasmosis in an Immunocompetent Host

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Cited by 6 publications
(3 citation statements)
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“…Of note, other rare case reports of cutaneous manifestations of underlying DH in non-HIV infected immunocompetent hosts have been reported by Indian authors, and in one of these cases, normalization of CD4 counts was documented after antifungal therapy, suggesting diminution in CD4 counts may be associated with DH itself. 8,9 Disseminated form of histoplasmosis generally presents with non- In the present case, the patient was from a non-endemic region and presented with multiple papulonodular lesions, fever, hepatoslenomegaly, and multiple lymphadenopathy. The diagnosis was first made on fine-needle aspiration of lymph nodes which was later confirmed by special stains along with skin and bone marrow biopsies.…”
Section: Discussionmentioning
confidence: 79%
“…Of note, other rare case reports of cutaneous manifestations of underlying DH in non-HIV infected immunocompetent hosts have been reported by Indian authors, and in one of these cases, normalization of CD4 counts was documented after antifungal therapy, suggesting diminution in CD4 counts may be associated with DH itself. 8,9 Disseminated form of histoplasmosis generally presents with non- In the present case, the patient was from a non-endemic region and presented with multiple papulonodular lesions, fever, hepatoslenomegaly, and multiple lymphadenopathy. The diagnosis was first made on fine-needle aspiration of lymph nodes which was later confirmed by special stains along with skin and bone marrow biopsies.…”
Section: Discussionmentioning
confidence: 79%
“…Oral ulcers are the most common mucocutaneous presentation, though nodules and vegetating plaques can also be seen in oral cavity. Cutaneous lesions of disseminated histoplasmosis are most commonly seen on the face, arms, and legs, and rarely acral area extremities, trunk, and genitalia (George et al 2015). The skin lesions are polymorphic comprising of erythematous or keratotic papule, pustule, plaque, ulcer, abscess, or cellulitis.…”
Section: Histoplasmosismentioning
confidence: 99%
“…Histoplasmosis is a systemic mycosis caused by Histoplasma capsulatum , a dimorphic fungus, first described in 1906 by Samuel Darling in Panama [1] , [2] . It has been isolated from soil contaminated with bird or bat droppings in endemic areas such as Brazil, North/Central of United States, central/western Africa and parts of Asia; it´s rare in Europe and frequently associated with patients from endemic areas who seek care in Europe or visited those countries in the past [3] , [4] , [5] , [6] , [7] , [8] . There are two varieties of H. capsulatum that are pathogenic to humans: H. capsulatum var.…”
Section: Introductionmentioning
confidence: 99%