Eccrine syringofibroadenoma is a very rare benign tumour of acrosyringium of eccrine sweat duct. Based on the evidences of known etiological factors, two forms have been proposed; reactive and nonreactive. Reactive forms are rarer, and on even rarer occasions, trauma complicated by secondary nonspecific infections may lead to the development of reactive eccrine syringofibroadenoma, as in our case. Here, we are documenting a case of reactive solitary eccrine syringofibroadenoma in a 65-year-old male presenting with coalescing, firm, pinkish, verrucous nodules and painful deep ulceration on the right sole preceded by trauma and secondary infection. Histopathologic revelation of distinctive microscopic findings confirmed the diagnosis in our case.
Background:Topical squaric acid dibutylester and diphenylcyclopropenone are still the most effective therapy for alopecia areata among widely available treatment options. Hence, it is important to know which one is more effective and safer between the two.Aims:The aim of this study was to compare topical squaric acid dibutylester and diphenylcyclopropenone for the treatment of alopecia areata in terms of their efficacy and side effects.Subjects and Methods:In the time period of January–March 2015, a total of 40 patients were selected for this study from the outpatient department of Rajendra Institute of Medical Sciences, Ranchi. After dropout of 16 patients, the remaining 24 patients were randomly divided into two groups; that is, group A for squaric acid dibutylester and group B for diphenylcyclopropenone. Each group received treatment for 6 months between March–November 2015. Their efficacy and side effects were compared.Statistical Test:Unpaired student t-test was performed. P < 0.05 was considered to be significant and 95% confidence interval was also used to evaluate the efficacy.Results:The mean values of percentage change in baseline severity of alopecia tool score for squaric acid dibutylester and diphenylcyclopropenone were 52.25 and 34.45, respectively. At 6 months, 95% confidence interval was 43.5–61% for group A and 25–44% for group B. In 58.33% of group A patients, A3 (50–74%) grade of improvement was observed, whereas in group B patients, it was 33.33%. A4 grade of improvement (75–99%) was also seen in 1 patient of group A. Minor side effects were seen in 2 patients of group A and 10 patients of group B. None of the group A patients showed major side effects, however, 2 patients suffered major side effects in group B.Conclusions:Between squaric acid dibutylester and diphenylcyclopropenone, squaric acid dibutylester is more efficacious. Further, frequencies of major and minor side effects are also lower than diphenylcyclopropenone.
HighlightsHydatid cyst of the breast is very rare.It is challenging to differentiate it from other tumoral lesions of the breast as it might mimic fibroadenoma, phyllodes tumors, chronic abscesses or even carcinoma.Only few reports of breast hydatid cyst are published and majority of the reported cases have been diagnosed postoperatively as it is not possible to reach definitive diagnosis with clinical examination and radiological investigations only.In spite of being very uncommon, it should be included in differential diagnosis of breast lumps for patients living in endemic areas.Surgical excision of the cyst is the treatment of choice.
Inflammatory linear verrucous epidermal nevus is a rare variant of nevoid linear inflammatory dermatoses which appear most often in first six months of life and persists for many years or even whole life. Clinically it often shares many features with linear psoriasis, linear porokeratosis and other linear dermatoses which can usually be differentiated by an established set of clinical and histopathological criteria. Herein we are reporting an interesting and rare case fulfilling all the clinical and histopathological criteria of inflammatory linear verrucous epidermal nevus in a 13 year old boy which uniquely revealed cornoid lamella on histopathology so we termed it as "porokeratotic variant of inflammatory linear verrucous epidermal nevus". To the best of our knowledge, only two such cases were reported previously in the literature and none from our country.
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