2018
DOI: 10.1039/c8ay01880d
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Ratiometric RNA aptamer/fluorophore complex for RNA synthesis detection

Abstract: Ratiometric RNA aptamer–fluorophore complex, Spinach2/DFHBI–CM, for quantifying the in vitro synthesis of RNA.

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Cited by 4 publications
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“…15 Because of their optical properties, triazoles have been used as uorescent linkers between two or more molecular fragments, showing an ambipolar behavior, depending on the substitution position. 16 The 1,2,3-triazole ring has been incorporated as a 3-, 4-, 5-and 7substituent into the coumarin heterocycle, acting as a linker between coumarin and other heterocycles, [17][18][19] glycosides, 20,21 polymeric chains; 22 or a phenyl ring. 23,24 All these SO conjugates share the non-planarity as a common feature through the incorporation of C(sp 3 ) or O(sp 3 ) atoms as part of the linker to improve solubility.…”
Section: Introductionmentioning
confidence: 99%
“…15 Because of their optical properties, triazoles have been used as uorescent linkers between two or more molecular fragments, showing an ambipolar behavior, depending on the substitution position. 16 The 1,2,3-triazole ring has been incorporated as a 3-, 4-, 5-and 7substituent into the coumarin heterocycle, acting as a linker between coumarin and other heterocycles, [17][18][19] glycosides, 20,21 polymeric chains; 22 or a phenyl ring. 23,24 All these SO conjugates share the non-planarity as a common feature through the incorporation of C(sp 3 ) or O(sp 3 ) atoms as part of the linker to improve solubility.…”
Section: Introductionmentioning
confidence: 99%