Rational Design and Enhanced Biocompatibility of a Dry Adhesive Medical Skin Patch

Kwak, Moon Kyu; Jeong, Hoon Eui; Suh, Kahp Y.

doi:10.1002/adma.201101694

Cited by 309 publications

(270 citation statements)

References 32 publications

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“…Recent studies on flexible mechanical and electrical sensing devices have demonstrated great potential in a wide range of applications, such as displays, 1,2 robotics, [3][4][5][6] in vitro diagnostics, [7][8][9] advanced therapies, 10,11 and energy harvesting. 2,[12][13][14] Such remarkable advances have been achieved through various solutions through the use of electrical active matrices on flexible rubberlike substrates to obtain various functions, such as high bendability, 15,16 ultrasensitivity, 7,17 transparency, 1,2,18-21 or wellestablished human-device interfaces.…”

Section: Introductionmentioning

confidence: 99%

Recent advances in flexible sensors for wearable and implantable devices

Pang

Lee

Suh

2013

J of Applied Polymer Sci

408

255

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Flexible devices are emerging as important applications for future display, robotics, in vitro diagnostics, advanced therapies, and energy harvesting. In this review, we provide an overview of recent achievements in flexible mechanical and electrical sensing devices, focusing on the properties and functions of polymeric layers. In the order of historical development, sensing platforms are classified into four types: electronic skins for robotics and medical applications, wearable devices for in vitro diagnostics, implantable devices for human organs or tissues for surgical applications, and advanced sensing devices with additional features such as transparency, self-power, and self-healing. In all of these examples, a polymer layer is used as a versatile component including a flexible structural support and a functional material to generate, transmit, and process mechanical and electrical inputs in various ways. We briefly discuss some outlooks and future challenges toward the next steps for flexible devices.

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Section: Introductionmentioning

confidence: 99%

Recent advances in flexible sensors for wearable and implantable devices

Pang

Lee

Suh

2013

J of Applied Polymer Sci

408

255

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“…This behavior is mainly attributed to the enlarged 3D microtips of octopus‐like sucker that can increase effective contact area to a combining surface. Therefore, the suction stress (negative pressure effect for wet condition) and molecular interactions (van der Waals for dry surface or capillary interaction for wet condition) between two engaged surfaces are amplified 6, 8, 28. Likewise, the adhesive with CR of 0.93 exhibited the highest adhesion performances among other samples for peeling off in both dry and underwater conditions (see Figure S6 for details, Supporting Information).…”

mentioning

confidence: 99%

Highly Adaptable and Biocompatible Octopus‐Like Adhesive Patches with Meniscus‐Controlled Unfoldable 3D Microtips for Underwater Surface and Hairy Skin

et al. 2018

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Adhesion capabilities of various skin architectures found in nature can generate remarkable physical interactions with their engaged surfaces. Among them, octopus suckers have unique hierarchical structures for reversible adhesion in dry and wet conditions. Here, highly adaptable, biocompatible, and repeatable adhesive patches with unfoldable, 3D microtips in micropillars inspired by the rim and infundibulum of octopus suction cup are presented. The bioinspired synthetic adhesives are fabricated by controlling the meniscus of a liquid precursor in a simple molding process without any hierarchical assemblies or additional surface treatments. Experimental and theoretical studies are investigated upon to increase the effective contact area between unfoldable microtips of devices, and enhance adhesion performances and adaptability on a Si wafer in both dry and underwater conditions (max. 11 N cm−2 in pull‐off strength) as well as on a moist pigskin (max. 14.6 mJ peeling energy). Moreover, the geometry‐controlled microsuckers exhibit high‐repeatability (over 100 cycles) in a pull‐off direction. The adhesive demonstrates stable attachments on a moist, hairy, and rough skin, without any observable chemical residues.

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“…These two types of controllable adhesives were inspired by aphids and geckos, respectively. Although the natural adhesives, especially the gecko type, have motivated engineers to develop artificial smart/controllable adhesives using relatively simple structures in diverse applications including climbing robots [44], bio-medical systems [45] and many others, none of these materials offers the same combination of remarkable properties that the natural gecko adhesive does [46][47][48]. So far, no report exists in which the sophisticated natural adhesives were used for any practical applications.…”

Section: Introductionmentioning

confidence: 99%

Geckoprinting: assembly of microelectronic devices on unconventional surfaces by transfer printing with isolated gecko setal arrays

Jeong

Kim

Song

et al. 2014

J. R. Soc. Interface.

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Developing electronics in unconventional forms provides opportunities to expand the use of electronics in diverse applications including bio-integrated or implanted electronics. One of the key challenges lies in integrating semiconductor microdevices onto unconventional substrates without glue, high pressure or temperature that may cause damage to microdevices, substrates or interfaces. This paper describes a solution based on natural gecko setal arrays that switch adhesion mechanically on and off, enabling pick and place manipulation of thin microscale semiconductor materials onto diverse surfaces including plants and insects whose surfaces are usually rough and irregular. A demonstration of functional 'geckoprinted' microelectronic devices provides a proof of concept of our results in practical applications.

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Rational Design and Enhanced Biocompatibility of a Dry Adhesive Medical Skin Patch

Cited by 309 publications

References 32 publications

Recent advances in flexible sensors for wearable and implantable devices

Recent advances in flexible sensors for wearable and implantable devices

Highly Adaptable and Biocompatible Octopus‐Like Adhesive Patches with Meniscus‐Controlled Unfoldable 3D Microtips for Underwater Surface and Hairy Skin

Geckoprinting: assembly of microelectronic devices on unconventional surfaces by transfer printing with isolated gecko setal arrays

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