Rational synthesis of Three-Layered plasmonic nanocomposites of copper Sulfide/Gold/Zinc-Doped Prussian blue analogues for improved photothermal disinfection and wound healing

Cao, Jun; Zhu, Wei; Shen, Aiguo; Hu, Jiming

doi:10.1016/j.jcis.2021.11.108

Cited by 13 publications

(7 citation statements)

References 45 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As it known to all, COL1, an important extracellular matrix of skin and with its synthesis promoted by TGF-β, is of great significance in skin wound repair [ 38 ]. It also confirmed that Zn 2+ contributed to the wound healing by improving the wound healing genes expression, which was also approved by other research work [ 43 , 44 ]. Besides, the Cu/Zn SOD activity was also investigated to evaluate the status of intracellular antioxidant system.…”

Section: Resultssupporting

confidence: 79%

Zinc-based metal organic framework with antibacterial and anti-inflammatory properties for promoting wound healing

Chen

Cai

Liu

et al. 2022

Regenerative Biomaterials

View full text Add to dashboard Cite

The synergistic effect of antibacterial and anti- inflammatory is needed to overcome the problem of wound healing difficulties. Based on the favorable antibacterial and anti- inflammatory effect of zinc ions (Zn2+) and the physicochemical properties of metal organic frameworks (MOFs), we prepared nanosized zinc-based MOF: Zn-BTC with the ability to slowly release Zn2+. In cellular levels, Zn-BTC possessed lower toxicity to fibroblasts and enhanced capacity of cell proliferation and migration. It also had good bactericidal effect on multiple drug resistant (MDR) bacteria by reducing 41.4% MRSA and 47.2% E. coli. In addition, Zn-BTC also displayed the ability of lowering the expression of antioxidant genes: superoxide dismutase 1 (SOD1), superoxide dismutase 2 (SOD2) and interleukin 6 (IL6), and enhancing the expression of wound healing genes: transforming growth factors-β (TGF-β) and type I collagen (COL1). Finally, it also demonstrated that Zn-BTC could effectively improve the skin wound healing of SD rats and had no toxicity on major organs. The favorable biocompatibility, antibacterial and anti- inflammatory properties of Zn-BTC gave a new insight of designing novel MOFs for promoting skin wound healing.

show abstract

Section: Resultssupporting

confidence: 79%

Zinc-based metal organic framework with antibacterial and anti-inflammatory properties for promoting wound healing

Chen

Cai

Liu

et al. 2022

Regenerative Biomaterials

View full text Add to dashboard Cite

show abstract

“…With the continuous development of PB core–shell nanoparticles, multilayer core–shell structures have also been designed. Hu et al used CuS NPs as the core to sequentially grow Au NPs and Zn–PBA NPs on its outside to form a composite structure of CuS@Au@Zn–PBA with a size of 200 nm, which assisted the Zn–PBA antibacterial through the LSPR coupling effect between CuS and Au 149 (Fig. 11F).…”

Section: Pb(pba) Compositesmentioning

confidence: 99%

Progress in the preparation of Prussian blue-based nanomaterials for biomedical applications

Lü

Zhu

et al. 2023

J. Mater. Chem. B

View full text Add to dashboard Cite

show abstract

“…[42]. (D): CuS@Au@ZnPBA for photothermal sterilization and accelerated incision healing [79]. Copyright application has been approved.…”

Section: Chemical Induction Promotes Wound Healingmentioning

confidence: 99%

“…There are issues to improve that include high cost, drug-related adverse effects, immunological rejection, and secondary harm to donor sites and wounds to enhance skin wound healing. Cao et al produced a drug-free three-layered photothermal bactericide comprising copper sulfide (CuS), gold (Au), and ZnPBA (CuS@Au@ZnPBA) from the inside out [ 79 ]. CuS@Au@ZnPBA generates local heat under photothermal conditions, and the released Zn 2+ can upregulate genes related to collagen deposition and promote bacterial ablation of wound infection in mice ( Figure 7 D).…”

Section: Application Of Enzyme Activity Of Pbnpsmentioning

confidence: 99%

See 1 more Smart Citation

Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor Applications

Liu

et al. 2022

Pharmaceuticals

View full text Add to dashboard Cite

In recent years, Prussian blue nanoparticles (PBNPs), also named Prussian blue nano-enzymes, have been shown to demonstrate excellent multi-enzyme simulation activity and anti-inflammatory properties, and can be used as reactive oxygen scavengers. Their good biocompatibility and biodegradability mean that they are ideal candidates for in vivo use. PBNPs are highly efficient electron transporters with oxidation and reduction activities. PBNPs also show considerable promise as nano-drug carriers and biological detection sensors owing to their huge specific surface area, good chemical characteristics, and changeable qualities, which might considerably increase the therapeutic impact. More crucially, PBNPs, as therapeutic and diagnostic agents, have made significant advances in biological nanomedicine. This review begins with a brief description of the synthesis methods of PBNPs, then focuses on the applications of PBNPs in tissue regeneration and inflammation according to the different properties of PBNPs. This article will provide a timely reference for further study of PBNPs as therapeutic agents.

show abstract

Rational synthesis of Three-Layered plasmonic nanocomposites of copper Sulfide/Gold/Zinc-Doped Prussian blue analogues for improved photothermal disinfection and wound healing

Cited by 13 publications

References 45 publications

Zinc-based metal organic framework with antibacterial and anti-inflammatory properties for promoting wound healing

Zinc-based metal organic framework with antibacterial and anti-inflammatory properties for promoting wound healing

Progress in the preparation of Prussian blue-based nanomaterials for biomedical applications

Synthesis of Prussian Blue Nanoparticles and Their Antibacterial, Antiinflammation and Antitumor Applications

Contact Info

Product

Resources

About