Re-emergence of echovirus type 13 infections in 2002 in Yamagata, Japan

Mizuta, Katsumi; Abiko, Chieko; Murata, Toshiro; Itagaki, Tsutomu; Katsushima, Noriko; Akiba, Tomoharu; Sakamoto, Michiyo; Ootani, Katsumi; Murayama, Shoko

doi:10.1016/s0163-4453(03)00081-1

Cited by 10 publications

(12 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Its sudden emergence as a predominant serotype was also observed in other countries: in the United States, E13 accounted for 24% of all reported HEV isolates in 2001, compared to 1.6% in 2000 [33]. In Japan, E13 had only been isolated once before 2001, during which 65 strains were isolated [34]. E13 was first identified in Spain during an aseptic meningitis outbreak in 2000 [35].…”

Section: Discussionmentioning

confidence: 71%

A Retrospective Overview of Enterovirus Infection Diagnosis and Molecular Epidemiology in the Public Hospitals of Marseille, France (1985–2005)

et al. 2011

View full text Add to dashboard Cite

Human enteroviruses (HEV) are frequent human pathogens and, associated in particular with large outbreaks of aseptic meningitis. Here, we have compiled a database of clinical HEV isolates from the Public Hospitals of Marseille, from 1985 to 2005. Amongst 654 isolates that could be characterized by complete sequencing of the VP1 gene, 98% belonged to species HEV-B; the most frequently isolated serotypes were Echovirus E30, E11, E7, E6 and E4. The high incidence of E30 and the recent emergence of E13 are consistent with reports worldwide and peak HEV isolation occurred mostly in the late spring and summer months. The proportion of echoviruses has decreased across the years, while that of coxsackieviruses has increased. Stool (the most frequent sample type) allowed detection of all identified serotypes. MRC5 (Human lung fibroblasts) cell line was the most conducive cell line for HEV isolation (84.9% of 10 most common serotype isolates, 96.3% in association with BGM (Buffalo green monkey kidney cells)). Previous seroneutralization-based serotype identification demonstrated 55.4% accuracy when compared with molecular VP1 analysis. Our analysis of a large number of clinical strains over 20 years reinforced the validity of VP1 serotyping and showed that comparative p-distance scores can be coupled with phylogenetic analysis to provide non-ambiguous serotype identification. Phylogenetic analysis in the VP1, 2C and 3D regions also provided evidence for recombination events amongst clinical isolates. In particular, it identified isolates with dissimilar VP1 but almost identical nonstructural regions.

show abstract

Section: Discussionmentioning

confidence: 71%

A Retrospective Overview of Enterovirus Infection Diagnosis and Molecular Epidemiology in the Public Hospitals of Marseille, France (1985–2005)

et al. 2011

View full text Add to dashboard Cite

show abstract

“…However, E13 had not been isolated clinically during the previous 20 years in Japan (9), and its isolation was rare until 2000. Thus, the outbreaks of aseptic meningitis caused by E13 seem to be a case of reemerging enterovirus infection (21,29).…”

mentioning

confidence: 99%

Molecular Epidemiology of Echoviruses 11 and 13, Based on an Environmental Surveillance Conducted in Toyama Prefecture, 2002-2003

Iwai

Yoshida

Matsuura

et al. 2006

Appl Environ Microbiol

View full text Add to dashboard Cite

Nineteen echovirus 11 (E11) and 12 E13 isolates were isolated from three rivers in Toyama Prefecture, Japan, during an environmental surveillance conducted from April 2002 to March 2003. The nucleotide sequences of E13 isolates were closely related to those from patients with aseptic meningitis, with less than 1.3% divergence in the VP1 region of the viral capsid gene, and belonged to the same clade responsible for a worldwide outbreak that started in 2000. In contrast, E11 isolates were clustered into three genomic groups and were not closely related to echovirus strains isolated from patients. These results suggest that the combination of both virus isolation from environmental sources and phylogenetic analysis could be complementary assessment approaches to trace prevalent and minor circulating enteroviruses in the human population.

show abstract

“…While echovirus types 11, 18, and 30 were frequently reported as causative agents of aseptic meningitis, E13 was rarely observed in Japan before 2001 (21) (19,31,32). These data suggested that E13 was present in these areas of Japan until 40 years ago but thereafter disappeared or circulated among extremely few inhabitants.…”

Section: Discussionmentioning

confidence: 99%

“…in 2001 (10,12). After that, the E13 outbreak spread throughout Japan in summer 2002 (8,14,19,33). We have previously reported that partial VP1 nucleotide sequences (703 bases) of isolates from patients with aseptic meningitis and three from river water samples in Toyama in 2002 showed more than 98.7% identity and belonged to the same genetic cluster as those that circulated worldwide in 2000 to 2002.…”

mentioning

confidence: 99%

Widespread Circulation of Echovirus Type 13 Demonstrated by Increased Seroprevalence in Toyama, Japan, between 2000 and 2003

Iwai

Yoshida

Obara

et al. 2010

Clin Vaccine Immunol

View full text Add to dashboard Cite

Re-emergence of echovirus type 13 infections in 2002 in Yamagata, Japan

Cited by 10 publications

References 11 publications

A Retrospective Overview of Enterovirus Infection Diagnosis and Molecular Epidemiology in the Public Hospitals of Marseille, France (1985–2005)

A Retrospective Overview of Enterovirus Infection Diagnosis and Molecular Epidemiology in the Public Hospitals of Marseille, France (1985–2005)

Molecular Epidemiology of Echoviruses 11 and 13, Based on an Environmental Surveillance Conducted in Toyama Prefecture, 2002-2003

Widespread Circulation of Echovirus Type 13 Demonstrated by Increased Seroprevalence in Toyama, Japan, between 2000 and 2003

Contact Info

Product

Resources

About