Reaction of aryl-substituted glycineamidines with oxalic acid derivatives

Synthesis of Novel α-Amino-N-substituted Thioacetimidates

“…Melting points were determined on a hot-stage microscope and are uncorrected. 1 H NMR spectra were recorded on a 300 MHz spectrometer using tetramethylsilane as the internal standard. The 13 C NMR spectra were recorded at 75 MHz on the same instrument with the solvent CDCl3 peak as the internal reference.…”

“…Compound 4e was crystallized from ethanol as white needles (63%); it was present as a 1:1 mixture of Bt 13 C NMR (CDCl3) [for both isomers] δ 22. 1,22.3,22.5,24.6,39.5,39.7,48.4,48.9,66.8,66.9,77.7,84.6,109.8,118.1,119.9,123.7,126.1,127.2,133.8,143.4,145.5. Anal.…”

“…13 C NMR (CDCl3) δ 53. 2,54.9,66.5,115.1,120.0,120.1,124.7,125.9,129.7,131.1,144.1,146.5,153.0,153.3. Anal.…”

“…13 C NMR (CDCl3) δ 53. 2,54.5,66.6,115.3,115.5,119.0,120.1,125.9,126.6,129.5,129.7,131.2,146.6,148.0,148.5,154.5. Anal.…”

“…13 C NMR (CDCl3) (at 60 °C) δ 21. 1,52.7,56.7,63.8,66.8,126.6,126.7,127.8,128.3,129.4,136.0,139.2,139.6,161.7. Anal.…”