Reaction of hexafluorobenzene with trimethylsilyl ethers

Multi‐Ferrocenyl Aryl Ethers – Applying Nucleophilic Aromatic Substitution Reactions to Aryl Fluorides

“…Several attempts to synthesize C 6 (OFc) 6 failed, because of the low thermal stability of 1 compared with C 6 H 5 OH . Compound 6e is the second example of a molecule bearing five ether and one fluoro substituent …”

Fluoride ion-catalyzed desilylative-defluorination for synthetic organic chemistry

“…Similar nucleophilic substitution of alkoxide anion equivalent 9 on an aromatic ring was achieved by the reaction of silyl ethers with hexafluorobenzene 7 in the presence of a catalytic amount of CsF as an initiator (Scheme 4) [4]. It was reported that the use of silyl ethers was more favorable for polyalkoxylation of 7 than alkali metal alkoxide.…”

Reactions of fluorinated hydroxy and epoxy ketones with tris(trimethylsilyl) phosphite

“…When Me 3 SiCl/Et 3 N, was used, only a poor yield of the silylated product SCHEME 1 2a was formed, but in the case of hexamethyldisilazane with a catalytic amount of sodium saccharin [3], the silyl ethers 2a and 2b were formed in high yield irrespective of the fluoroalkyl chain length (Scheme 1).…”

“…The filtrate was dried in vacuo, giving 6a as very hygroscopic solid. 9,9,9,8,8,7,7,6,6,5,5,4,4- 3 P, 40%], 1.0 (s, 7A) and 1.7 (s, 7B, 60%). After 1 day: d ‫ס‬ 1.0 and 1.7 (60%), 114.0 (40%).…”