Abstract. Leucaena leucocephala is a small tropical tree used for a variety of purposes in agriculture, land management and homeopathic medicine. Quercetin, a flavonoid, was isolated and characterised from extracts of leaves of L. leucocephala and its effects on egg hatching and juvenile mortality of Meloidogyne incognita were investigated at 0.8, 0.4 and 0.2% in vitro. The compound was highly toxic to eggs and juveniles of the nematode at the three rates tested.