Reactions with Hydrazonoyl Halides. 31. Synthesis of Some New Pyrrolidino[3,4-c]pyrazolines, Pyrazoles, and Pyrazolo[3,4-d]pyridazines

Abstract

Pyrrolidino[3,pyrazoline and pyrazole derivatives were synthesized via reactions of a substituted hydrazonoyl bromide with N-arylmaleimides and active methylene reagents, respectively. Synthesized pyrazoles were reacted with hydrazine hydrate to give the corresponding pyrazolo [3,4-d]pyridazines.

Synthesis and Antimicrobial Evaluation of Some New Organic Tellurium Compounds Based on Pyrazole Derivatives

“…The literature confirms that pyrazole derivatives are used as antimicrobial, antifungal, antitumor, anti-inflammatory, and antioxidant compounds [ 3 ]. A common method for the synthesis of the substituted pyrazoles includes the cyclization reaction of α,β-unsaturated ketones (chalcones) with hydrazines [ 4 , 5 ].…”

Reactions with Hydrazonoyl Halides 421: Synthesis of Some New 2,3-Dihydro-1,3,4thiadiazoles, 2,3-Dihydro-1,3,4-selenadiazoles and Triazolino[, ]pyrimidines

“…5 Also hydrazonoyl halides have been widely for the synthesis of heterocyclic compounds. [6][7][8][9][10] We report here the synthesis of triazolo [4,3-a]pyrimidines, 2,3-dihydro-1,3,4-thiadiazoles, 2,3-dihydro-1,3,4-selenadiazoles, and unsymmetrical azines.…”

Microwave-Assisted Synthesis of Some 3,5-Arylated 2-Pyrazolines

“…In recent years, a significant portion of research in heterocyclic chemistry has been devoted to 2-pyrazolines containing different aryl groups as substituents, as evident from the literature [ 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 ]. We have recently reported on the synthesis of some newly 3,5-naphthylated 2-pyrazolines which exhibit efficient antimicrobial activity against a variety of test organisms [ 8 ].…”