Reactive oxygen species as causative agents in the ichthyotoxicity of the red tide dinoflagellate Cochlodinium polykrikoides

Kim, Chang-Sook; Lee, Sam Geun; Lee, Chang Kyu; Kim, Hak Gyoon; Jung, Jin

doi:10.1093/plankt/21.11.2105

Cited by 174 publications

(194 citation statements)

References 21 publications

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“…Reports of HAB species that produce significant levels of ROS include H. akashiwo (Twiner and Trick 2000), Chattonella spp. (Tanaka et al 1992), Olisthodiscus luteus (Kim et al 1999b), as well as the coccolithophorid Hymenomonas carterae (Palenik et al 1987) and the dinoflagellate Cochlodinium polykrikoides (Kim et al 1999a). In this study, we have shown that four geographically distinct H. akashiwo isolates have different levels of H 2 O 2 production.…”

Section: Discussionmentioning

confidence: 60%

Toxic effects of Heterosigma akashiwo do not appear to be mediated by hydrogen peroxide

Twiner

Dixon

Trick

2001

Limnology & Oceanography

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The ichthyotoxic red tide organism Heterosigma akashiwo (Raphidophyceae) has been associated with fish kill events within the aquaculture industry for many years. The precise toxicological mechanism involved in these fish kills is unclear; however, much research attention has focused on the production of reactive oxygen species (ROS) by these toxic algae. In this study, we investigated the production of hydrogen peroxide (

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Section: Discussionmentioning

confidence: 60%

Toxic effects of Heterosigma akashiwo do not appear to be mediated by hydrogen peroxide

Twiner

Dixon

Trick

2001

Limnology & Oceanography

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“…High levels of H 2 O 2 were produced in the exponential growth phase of C. polykrikoides (~ 6,000 cells/ml) under laboratory conditions (Kim et al, 1999a; and concomitant lipid peroxidation of fish gill tissue was observed. This lends further support to the hypothesis that damage was mediated though radical-dependent oxidation.…”

Section: Introductionmentioning

confidence: 98%

“…(Shimada et al, 1991(Shimada et al, , 1993Oda et al, 1992aOda et al, , 1992bOda et al, , 1994Oda et al, , 1995Oda et al, , 1997Kim et al, 1999a). No conclusive scientific evidence is, however, available to prove any of these inferences.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant responses and lipid peroxidation in gills and erythrocytes of fish (Rhabdosarga sarba) upon exposure to Chattonella marina and hydrogen peroxide: Implications on the cause of fish kills

Woo

Liu

et al. 2006

Journal of Experimental Marine Biology and Ecology

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Chattonella marina, a red tide or harmful algal bloom species, has caused mass fish kills and serious economic loss worldwide, and yet its toxic actions remain highly controversial. Previous studies have shown that this species is able to produce reactive oxygen species (ROS), and therefore postulated that ROS are the causative agents of fish kills. The present study investigates antioxidant responses and lipid peroxidation in gills and erythrocytes of fish (Rhabdosarga sarba) upon exposure to C. marina, compared with responses exposed to equivalent and higher levels of ROS exposure.Even though C. marina can produce a high level of ROS, gills and erythrocytes of sea bream exposed to C. marina for 1 to 6 h showed neither significant induction of antioxidant enzymes nor lipid peroxidation. Antioxidant responses and oxidative damage did not occur as fish mortality began to occur, yet could be induced upon exposure to artificially supplied ROS levels an order of magnitude higher. The result of this study implies that ROS produced by C. marina is not the principal cause of fish kills.

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“…One of the major killers of farmed fish is considered to be the formation of superoxide anion radical (O -2 ) by Chatonella antiqua and Heterosigma akashiwo (Tanaka et al, 1994;Oda et al, 1997), and Cochlodinium polykrikoides (Kim et al, 1999). The mechanism of death is considered by some to be mucus stripping from the gills of the fish, which leads to osmoregulatory dysfunction and ultimately to death.…”

Section: Therapeuticsmentioning

confidence: 99%

Action Plan for Monitoring, Mitigation and Management of Harmful Algal Blooms in the Coastal Waters of Oman

Alkindi

Al-Ghelani

Amer

et al. 2007

SQU Journal for Science

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: The Gulf of Oman, an ecologically and economically rich ecosystem, is frequently impacted by occurrences of harmful algal blooms. Recent studies indicate an increase in the number of causative species and harmful impacts. Many red tide incidents in Oman have been found leading to hypoxia. The frequent bloom forming species here are Karenia selliformis, Nitzschia pungens, Prorocentrum arabianum and Trichodesmium erythraeum. We review work carried out in this area, and we propose here a Management Action Plan for not only an effective monitoring system for harmful algal blooms (HABs), but also mitigation of their adverse impacts and rapid response system.

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Reactive oxygen species as causative agents in the ichthyotoxicity of the red tide dinoflagellate Cochlodinium polykrikoides

Cited by 174 publications

References 21 publications

Toxic effects of Heterosigma akashiwo do not appear to be mediated by hydrogen peroxide

Toxic effects of Heterosigma akashiwo do not appear to be mediated by hydrogen peroxide

Antioxidant responses and lipid peroxidation in gills and erythrocytes of fish (Rhabdosarga sarba) upon exposure to Chattonella marina and hydrogen peroxide: Implications on the cause of fish kills

Action Plan for Monitoring, Mitigation and Management of Harmful Algal Blooms in the Coastal Waters of Oman

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