Reactivity of novel ethyl cyanoacrylate and 6-hydroxyhexyl acrylate adhesive mixtures and their influence on adhesion and thermal stability

Abstract

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Effects of methoxy polyethylene glycol‐polycaprolactone block copolymers and silica nanoparticles on the mechanical, tissue affinity and antibacterial properties of n‐butyl cyanoacrylate adhesive

“…MPEG, PCL, and MP‐3 were tested in the temperature range of 20–200°C at a heating rate of 10°C min −1 under a nitrogen atmosphere (flow rate: 20 mL min −1 ) 30 ; while cured adhesive samples were tested in the temperature range of −50 to 150°C under the same conditions and then cooled to −50°C. After that, the glass transition temperature ( T g ) of the polymer was determined by heating the polymer from −50 to 300°C at a heating rate of 10°C min −1 12 …”

“…MPEG, PCL, and MP-3 were tested in the temperature range of 20-200 C at a heating rate of 10 C min À1 under a nitrogen atmosphere (flow rate: 20 mL min À1 ) 30 ; while cured adhesive samples were tested in the temperature range of À50 to 150 C under the same conditions and then cooled to À50 C. After that, the glass transition temperature (T g ) of the polymer was determined by heating the polymer from À50 to 300 C at a heating rate of 10 C min À1 . 12 The weight fractions of SNPs, cured BCA and 0.5SNPs/0.5MP-3 were measured using a Netzsch TG 209F1 in the temperature range of 25-300 C at a heating rate of 10 C min À1 under a nitrogen atmosphere (flow rate: 20 mL min À1 ). 31 F I G U R E 1 Synthesis of MPEG-co-PCL by ring-opening polymerization of ε-CL monomers.…”

“…Currently, one of the most effective methods to improve the flexibility of cyanoacrylates is to add non‐toxic plasticizing and toughening modifiers. For instance, different amounts of 6‐hydroxyphenyl acrylate were added to reduce the stiffness of ethyl cyanoacrylate 12 . The addition of high‐molecular weight polymethacrylate could improve the tensile shear strength and stress relaxation of ethyl cyanoacrylate, 13,14 and the addition of nanostructured acrylate polyhedral oligomeric silsesquioxane to octyl cyanoacrylate significantly improved the flexural strength of adhesives 15 .…”

“…For instance, different amounts of 6-hydroxyphenyl acrylate were added to reduce the stiffness of ethyl cyanoacrylate. 12 The addition of high-molecular weight polymethacrylate could improve the tensile shear strength and stress relaxation of ethyl cyanoacrylate, 13,14 and the addition of nanostructured acrylate polyhedral oligomeric silsesquioxane to octyl cyanoacrylate significantly improved the flexural strength of adhesives. 15 By and large, this is an efficient and low-cost approach.…”

Rapid coating of millimeter‐scale hydrogel capsules with interfacial polymerization

“…Poly(ethyl cyanoacrylate) (PECA) is synthesized via anionic polymerization of ethyl cyanoacrylate (ECA) which is recognized as one of the most reactive monomers, 22 employing a nucleophilic attack mechanism 23 . Notably, the polymerization of ECA occurs rapidly at room temperature, in the presence of weak basic materials or minute quantities of water, 24,25 as shown in Figure 1. Since the good biodegradability and drug compatibility of PECA, ECA has been extensively used in surgery for tissue adhesive and hemostatic substance 26 .…”