2021
DOI: 10.1097/ta.0000000000003059
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Real-time bedside management and titration of partial resuscitative endovascular balloon occlusion of the aorta without an arterial line: Good for pressure, not for flow!

Abstract: BACKGROUND: Partial resuscitative endovascular balloon occlusion of the aorta (pREBOA) attempts to minimize ischemia/reperfusion injury while controlling hemorrhage. There are little data on optimal methods to evaluate and titrate partial flow, which typically requires invasive arterial line monitoring. We sought to examine the use of a miniaturized handheld digital pressure device (COMPASS; Mirador Biomedical, Seattle, WA) for pREBOA placement and titration of flow. METHODS:Ten swine underwent standardized he… Show more

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Cited by 7 publications
(10 citation statements)
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“…In a recent feasibility study in humans, use of partial REBOA versus complete occlusion trended toward fewer ventilator days, less dialysis, and less vasopressor requirement. 26 Future investigations could continue evaluating the use of the CD in partial REBOA models during real-time pressure titration, such as that performed by Carr et al 11 The primary limitation of this study is the small sample size, precluding any meaningful comparison of values between animals that survived until and those that died before the 120-minute time point. However, as the primary objective of this study was to demonstrate the feasibility of single operator damage-control resuscitation with a REBOA catheter for noncompressible truncal hemorrhage using a CD, we feel that we were able to achieve this endpoint with our sample size of animals while minimizing unnecessary animal use.…”
Section: Discussionmentioning
confidence: 97%
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“…In a recent feasibility study in humans, use of partial REBOA versus complete occlusion trended toward fewer ventilator days, less dialysis, and less vasopressor requirement. 26 Future investigations could continue evaluating the use of the CD in partial REBOA models during real-time pressure titration, such as that performed by Carr et al 11 The primary limitation of this study is the small sample size, precluding any meaningful comparison of values between animals that survived until and those that died before the 120-minute time point. However, as the primary objective of this study was to demonstrate the feasibility of single operator damage-control resuscitation with a REBOA catheter for noncompressible truncal hemorrhage using a CD, we feel that we were able to achieve this endpoint with our sample size of animals while minimizing unnecessary animal use.…”
Section: Discussionmentioning
confidence: 97%
“…In a recent feasibility study in humans, use of partial REBOA versus complete occlusion trended toward fewer ventilator days, less dialysis, and less vasopressor requirement 26 . Future investigations could continue evaluating the use of the CD in partial REBOA models during real-time pressure titration, such as that performed by Carr et al 11 …”
Section: Discussionmentioning
confidence: 99%
See 2 more Smart Citations
“…Distal pressure measurement, which can be measured with a conventional arterial line or a portable handheld device (the COMPASS device; Mirador Biomedical, Seattle, WA) 23 , is a clinically available parameter for the titration of P-REBOA. However, distal pressure does not necessarily reflect distal arterial flow or organ perfusion 24 . Balloon volume can reflect distal organ perfusion and is a clinically usable parameter, which are the strengths of the P-REBOA titration using percent balloon volume.…”
Section: Discussionmentioning
confidence: 99%