Real-time detection of fast and thermal neutrons in radiotherapy with CMOS sensors

Arbor, N.; Higueret, S.; Elazhar, Halima; Combe, R.; Meyer, P.; Dehaynin, N.; Taupin, Florence; Husson, D.

doi:10.1088/1361-6560/aa5bc9

Cited by 7 publications

(4 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A PTW Semiflex 31010 ion chamber (sensitive volume of 0.125 cm 3 ) was used to measure the percentage depth dose (PDD) and the lateral dose profile (at 20 mm, 50 mm and 100 mm) in a water tank. The measurements were done with a Source Surface Distance (SSD) of 100 cm and a 10×10 cm 2 field (corresponding to the most common field size for breast cancer radiotherapy) with a full opening MLC [24]. The PDD and the dose profiles were only used as a first step of the validation of VMAT simulation in order to check the general LINAC geometry and to define the optimal electron beam parameters (E = 6.0 MeV, FWHM = 1.0 mm).…”

Section: We Present a New Open Source Tool Developed In Collaborationmentioning

confidence: 99%

A GATE/Geant4 Monte Carlo toolkit for surface dose calculation in VMAT breast cancer radiotherapy

Arbor¹,

Gasteuil²,

Noblet³

et al. 2019

Physica Medica

Self Cite

View full text Add to dashboard Cite

The accuracy of superficial dose calculations for breast cancer treatments with Volumetric Modulated Arc Therapy (VMAT) is of major importance. For target volumes close to the surface, the inverse dosimetric planning can lead to very high fluences in the build-up region to properly cover the volume to be treated. Various radiotherapy modalities are currently used in parallel with additional protocols to enable a better control on the dose delivery (bolus, target volume margins). One of the difficulties currently facing medical physicists is the lack of available tools to test the impact of these different solutions on the superficial dose distribution. We present a new open source toolkit to assist medical physicists in evaluating the 3D distributions of superficial dose in VMAT breast cancer treatments. This tool is based on the GATE Monte Carlo software, a Geant4 application dedicated to medical physics. A set of macros has been developed to simulate in an easy way a full VMAT plan from the information available in the DICOM-RT files (image, plan, structure and dose). The toolkit has been tested on a 6 MV Varian NovalisTx TM accelerator. The paper presents a precise comparison of 3D surface dose distributions from experimental measurements (EBT3 films), TPS (Varian Eclipse) and Monte Carlo simulation (GATE). The comparison made it possible to highlight both the TPS biases for the surface dose calculation and the good performances of the developed toolkit. The simulation of surface dose distributions on a real patient has also been performed to illustrate the potential clinical applications.

show abstract

Section: We Present a New Open Source Tool Developed In Collaborationmentioning

confidence: 99%

A GATE/Geant4 Monte Carlo toolkit for surface dose calculation in VMAT breast cancer radiotherapy

Arbor¹,

Gasteuil²,

Noblet³

et al. 2019

Physica Medica

Self Cite

View full text Add to dashboard Cite

show abstract

“…The first one, called AlphaRad [19], EPJ Web of Conferences 170, 09001 (2018) https://doi.org/10.1051/epjconf/201817009001 ANIMMA 2017 Fig. 3.…”

Section: Spectrummentioning

confidence: 99%

Conception of a New Recoil Proton Telescope for Real-Time Neutron Spectrometry in Proton-Therapy

et al. 2018

Self Cite

View full text Add to dashboard Cite

Abstract-Neutrons are the main type of secondary particles emitted in proton-therapy. Because of the risk of secondary cancer and other late occurring effects, the neutron dose should be included in the out-of-field dose calculations. A neutron spectrometer has to be used to take into account the energy dependence of the neutron radiological weighting factor. Due to its high dependence on various parameters of the irradiation (beam, accelerator, patient), the neutron spectrum should be measured independently for each treatment.The current reference method for the measurement of the neutron energy, the Bonner Sphere System, consists of several homogeneous polyethylene spheres with increasing diameters equipped with a proportional counter. It provides a highresolution reconstruction of the neutron spectrum but requires a time-consuming work of signal deconvolution. New neutron spectrometers are being developed, but the main experimental limitation remains the high neutron flux in proton therapy treatment rooms. A new model of a real-time neutron spectrometer, based on a Recoil Proton Telescope technology, has been developed at the IPHC. It enables a real-time high-rate reconstruction of the neutron spectrum from the measurement of the recoil proton trajectory and energy. A new fast-readout microelectronic integrated sensor, called FastPixN, has been developed for this specific purpose.A first prototype, able to detect neutrons between 5 and 20 MeV, has already been validated for metrology with the AMANDE facility at Cadarache. The geometry of the new Recoil Proton Telescope has been optimized via extensive Geant4 Monte Carlo simulations. Uncertainty sources have been carefully studied in order to improve simultaneously efficiency and energy resolution, and solutions have been found to suppress the various expected backgrounds. We are currently upgrading the prototype for secondary neutron detection in proton therapy applications.

show abstract

“…A remote measurement device was developed for low-energy radiation detection by combining CMOS radiation detection and ZigBee wireless transmission technology [ 9 ]. Moreover, MAPSs are sensitive to neutrons, and their response signals are dependent on neutron energy and injection volume [ 10 , 11 , 12 ].…”

Section: Introductionmentioning

confidence: 99%

Real-Time Monitoring Method for Radioactive Substances Using Monolithic Active Pixel Sensors (MAPS)

Han

Youjun

2022

Sensors

View full text Add to dashboard Cite

This study presents a real-time monitoring technique for radioactive substances that meets safety management needs. We studied the accumulation characteristics of radiation response signals of monolithic active pixel sensors (MAPSs) based on their response and discrimination ability to gamma (γ) photon or neutron radiation. The radiation status of the radioactive substances was determined by monitoring the accumulation data of radiation responses. As per the results, Am-Be and 252Cf radiation response signals are primarily concentrated in the range of 0–70 pixels. Response signals of 60Co and 137Cs γ-ray were concentrated in two regions; there was a peak in the region with a pixel value of less than 50, and a plateau in the region with a pixel value of more than 75. Therefore, the results are able to discriminate between spectra. Furthermore, we designed a radioactivity monitoring system that is able to examine multiple radioactive materials. Its working principle is that a change in the accumulation of radioactivity monitoring data indicates a radiation change during the last accumulation cycle. This study provides vital technical support for the long-term supervision of radioactive substances.

show abstract

Real-time detection of fast and thermal neutrons in radiotherapy with CMOS sensors

Cited by 7 publications

References 57 publications

A GATE/Geant4 Monte Carlo toolkit for surface dose calculation in VMAT breast cancer radiotherapy

A GATE/Geant4 Monte Carlo toolkit for surface dose calculation in VMAT breast cancer radiotherapy

Conception of a New Recoil Proton Telescope for Real-Time Neutron Spectrometry in Proton-Therapy

Real-Time Monitoring Method for Radioactive Substances Using Monolithic Active Pixel Sensors (MAPS)

Contact Info

Product

Resources

About