The PMD Camboard Picoflexx Time-of-Flight (ToF) camera is evaluated against the Microsoft Kinect V2 to assess its performance in the context of markerless motion capture system for human body kinematics measurements. Various error sources such as the warm-up time, the depth distortion, the amplitude related error, the signal-to-noise ratio, and limitations such as their dependence on the illumination pattern and on the target distance, are studied and compared. The Picoflexx device is also compared to the Kinect V2 in relation to the quality of shape reconstructions, to assess its adequateness in modeling human body segments, and human body kinematics measurements. The final result of this paper is definitely useful to the research community, demonstrating that, even if the Picoflexx performs lower than the Kinect concerning the measurement performances, its behavior in estimating the volume of the body segments, the angles at the joints for human body kinematics, and the angle at the ankle in assisted walking applications is definitely satisfactory. These results are extremely significant to obtain accurate estimates of the parameters of the human body models in markerless motion capture applications, especially in laboratory-free environments, where compactness, lightweight, wireless connection, and low-power consumption are of outmost importance.