Real-Time Lung Tumour Motion Modeling for Adaptive Radiation Therapy Using Lego Mindstorms

Guidi, G.; Maffei, N.; Ciarmatori, A.; Mistretta, Marina; Gottardi, Giovanni; Costi, T.; Vecchi, C.; Baldazzi, G.; Bertoni, F.

doi:10.1142/s0219519415400199

Cited by 4 publications

(5 citation statements)

References 20 publications

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“…In [ 39 ], an anthropomorphic phantom is built using LEGO Mindstorms EV3 for Adaptive Radiation Therapy (ART) purposes in order to simulate the breathing processes in the lung district during treatments. The humanoid phantom is tested in clinical practice, where breaths and CT studies of 12 patients are analyzed.…”

Section: Lego Mindstorms: From Kids To Researchersmentioning

confidence: 99%

A Novel Real-Time MATLAB/Simulink/LEGO EV3 Platform for Academic Use in Robotics and Computer Science

Sánchez

Rosillo

Mora

et al. 2021

Sensors

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Over the last years, mobile robot platforms are having a key role in education worldwide. Among others, LEGO Robots and MATLAB/Simulink are being used mainly in universities to improve the teaching experience. Most LEGO systems used in the literature are based on NXT, as the EV3 version is relatively recent. In contrast to the previous versions, the EV3 allows the development of real-time applications for teaching a wide variety of subjects as well as conducting research experiments. The goal of the research presented in this paper was to develop and validate a novel real-time educational platform based on the MATLAB/Simulink package and the LEGO EV3 brick for academic use in the fields of robotics and computer science. The proposed framework is tested here in different university teaching situations and several case studies are presented in the form of interactive projects developed by students. Without loss of generality, the platform is used for testing different robot path planning algorithms. Classical algorithms like rapidly-exploring random trees or artificial potential fields, developed by robotics researchers, are tested by bachelor students, since the code is freely available on the Internet. Furthermore, recent path planning algorithms developed by the authors are also tested in the platform with the aim of detecting the limits of its applicability. The restrictions and advantages of the proposed platform are discussed in order to enlighten future educational applications.

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Section: Lego Mindstorms: From Kids To Researchersmentioning

confidence: 99%

A Novel Real-Time MATLAB/Simulink/LEGO EV3 Platform for Academic Use in Robotics and Computer Science

Sánchez

Rosillo

Mora

et al. 2021

Sensors

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“…Automated liquid handling systems are used day by day to develop protocols and for reliability in laboratory fields such as synthetic biology, microbiology, or genetics. LEGO Mindstorms, which is widely used in the programming of complex systems and offers a wide range of work, provides opportunities such as designing machine prototypes in the field of robotics (Guidi, 2015). It has been reported in the literature that liquid-processing LEGO robotic systems can be used in biotechnology experiments (Gerber, 2017).…”

Section: Introductionmentioning

confidence: 99%

Autonomous Remotely Controlled Closed System Transgenic Cell Technologies Robot: CRISPR.BOT

Erkek

Gulden

Sert

et al. 2022

Preprint

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In manually advancing experimental processes, the stages may be long-term and need to be repeated. Human errors with the repetition of the steps turn into a time-consuming and high-cost for the experiment processes. For this reason, autonomous liquid processing systems are promising technologies. However, in addition to the high cost of fully automatic systems, their maintenance is also quite expensive. Furthermore, conventional systems usually require system-specific protocols and laboratory equipment. Here, we aimed to show that the autonomous robotic systems may provide a closed and error-free molecular biology bench to perform genetic engineering automatically, quickly, and practically 7-24. In this way, researchers can save time from repetitive experiment processes and perform BSL3 experiments including pathogens without human contact. In this study, we built CRISPR.BOT robotic systems to perform Green Fluorescent Protein (GFP) encoding plasmid DNA transfer into bacteria, lentiviral transduction of the gene-of-interests including GFP encoding gene and CRISPR-Cas9 with gRNAs genetic editing system to a human cell line. Furthermore, we showed that CRISPR.BOT system achieved to accomplish single-cell subcloning of GFP+ CRISPR-gRNA+ cells with 90-100% purity. This study suggests that CRISPR.BOT-like approaches may reduce manpower in a safely closed bench in which molecular biology and genetic engineering can be done by robots in a closed system without touching pathogenic microorganisms (virus or bacteria, for example, SARS CoV-2 virus). Furthermore, LEGO Mindstorms robots showed to have the potential to be used in daily laboratory routines with their cost-effectiveness reduced by up to 50 times compared to normal commercial robots.

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“…For instance, there are some studies using LabVIEW in the fields such as education [1][2][3][4], health [5,6], food and beverage control [7,8], astronomy [9] and image processing [8,10] In addition, studies using more than one sensor [11,12], real-time systems [5,13], studies on nuclear power plants [14], test/measurement device design that requires high precision [15][16][17], non-contact motion detection systems [18] and electromagnetic imaging [19] are other applications of LabVIEW.…”

Section: Introductionmentioning

confidence: 99%

A simulation object with LabVIEW: simultimeter (simulated multimeter)

Çoramık¹

2020

Phys. Educ.

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Teaching materials used in distance education are generally obtained from the internet as ready-made by teachers. Materials such as simulation, animation and presentation are usually limited to the frame drawn by the creator and do not allow changes outside this limit. In addition, many of these types of materials do not have a feedback mechanism. The multimeter is one of the basic tools used in all courses such as physics laboratory, electronics laboratory, electrical laboratory and even chemistry laboratory, which are practiced in the fields of science and engineering. Students make many mistakes while using the multimeter. For this purpose, in this study, it is aimed to design a digital multimeter used in the laboratories of the basic courses at high school and university level as a simulation object. This simulation program is called SiMultimeter (simulated multimeter). The other aims of the study are that the simulation gives feedback to the users and that it can be installed on the computer with .exe extension without the need for internet connection.

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Real-Time Lung Tumour Motion Modeling for Adaptive Radiation Therapy Using Lego Mindstorms

Cited by 4 publications

References 20 publications

A Novel Real-Time MATLAB/Simulink/LEGO EV3 Platform for Academic Use in Robotics and Computer Science

A Novel Real-Time MATLAB/Simulink/LEGO EV3 Platform for Academic Use in Robotics and Computer Science

Autonomous Remotely Controlled Closed System Transgenic Cell Technologies Robot: CRISPR.BOT

A simulation object with LabVIEW: simultimeter (simulated multimeter)

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