2018
DOI: 10.1016/j.jddst.2018.04.018
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Real-time monitoring of the tablet-coating process by near-infrared spectroscopy - Effects of coating polymer concentrations on pharmaceutical properties of tablets

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Cited by 31 publications
(8 citation statements)
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“…Dissolution tests of the test tablets were performed in 900 mL of water in a 1000 mL capacity round-bottomed flask at 37.0 ± 0.5 °C with stirring at 100 rpm using a puddle in an automatic dissolution test apparatus (Type DT-610, JASCO Co., Ltd., Tokyo, Japan; Japanese Pharmacopeia 18). Dissolved drug concentrations were automatically measured by ultraviolet (UV) absorption at 271 nm at predetermined time intervals in quartz flow cells with a length of 10 mm using a UV–visible spectrophotometer [ 33 ]. All measurements were repeated thrice.…”
Section: Methodsmentioning
confidence: 99%
“…Dissolution tests of the test tablets were performed in 900 mL of water in a 1000 mL capacity round-bottomed flask at 37.0 ± 0.5 °C with stirring at 100 rpm using a puddle in an automatic dissolution test apparatus (Type DT-610, JASCO Co., Ltd., Tokyo, Japan; Japanese Pharmacopeia 18). Dissolved drug concentrations were automatically measured by ultraviolet (UV) absorption at 271 nm at predetermined time intervals in quartz flow cells with a length of 10 mm using a UV–visible spectrophotometer [ 33 ]. All measurements were repeated thrice.…”
Section: Methodsmentioning
confidence: 99%
“…Alternatively, a range of spectroscopic methods suitable for in-line monitoring of the coating thickness have been investigated, including near-infrared spectroscopy (NIRS), Raman spectroscopy (RS), terahertz pulsed imaging (TPI), and optical coherence tomography (OCT) [6][7][8][9]. NIRS and Raman techniques measure the coating thickness indirectly by correlating the spectral response of the probing lights to the amount of coating material.…”
Section: An Overview Of Coating Measurement and Monitoring Methodsmentioning
confidence: 99%
“…In addition, thus far, NIR spectroscopy has also been used for monitoring different manufacturing processes such as blending, 17 tableting, 18 and coating. 19…”
Section: Introductionmentioning
confidence: 99%