1997
DOI: 10.1006/abio.1997.2105
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Real-Time Observation of Affinity Reactions Using Grating Couplers: Determination of the Detection Limit and Calculation of Kinetic Rate Constants

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Cited by 41 publications
(35 citation statements)
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“…Keeping in mind that ϭ K s , we may now integrate Eq. [3] forward in time to obtain the total adsorbed density.…”
Section: Theorymentioning
confidence: 99%
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“…Keeping in mind that ϭ K s , we may now integrate Eq. [3] forward in time to obtain the total adsorbed density.…”
Section: Theorymentioning
confidence: 99%
“…In Eq. [3], the partial derivative is taken at constant K s . ⌽ (°) is approximated by one of its very accurate interpolants,…”
Section: Theorymentioning
confidence: 99%
See 1 more Smart Citation
“…[1][2][3][4][5] The PSi optical sensing features were based on the changes of its photonic properties, such as photoluminescence or reflectance, on exposure to the gaseous or liquid substances. [6][7] Two main optical transduction methods for label-free biosensors were both optical interferometric methods based on interferometers, 8 evanescent wave devices, 9 and grating couplers, 10 and surface plasmon methods based on metal films, 11 and colloids. 12 However they required a tedious work and very complex preparation during analysis.…”
Section: Introductionmentioning
confidence: 99%
“…Thus, the lowest detection limit for a compound depends on the sensitivity of the device to monitor small changes in refractive index and on the compound's molecular weight. Changes in refractive index are directly proportional to the mass loading due to the binding of the analyte to the waveguide surface (18,20).…”
Section: Immunosensor Systems Requiring No Labelsmentioning
confidence: 99%