Real-Time Two-Dimensional Imaging of Potassium Ion Distribution Using an Ion Semiconductor Sensor with Charged Coupled Device Technology

Real-time monitoring of inhibitory effects on glutamate-induced neurotransmitter release using a potassium ion image sensor

“…The K + image sensor was fabricated by coating a charge-coupled device ion-image sensor with a K +-sensitive PVC membrane 10 . The sensing area of the charge-transfer ion-image sensor consisted of a Si 3 N 4 /SiO 2 /p-Si structure.…”

“…In addition, a 32 × 32 pixel array of enzymetagged image sensors has been fabricated to directly measure physiologically active substances, such as acetylcholine 9 . Furthermore, a 32 × 32 pixel array of potassium ion-and sodium ion-sensitive image sensors has been successfully fabricated by applying an ion-selective membrane to a sensor; this sensor enables real-time imaging of K + and Na + concentrations in solution 10,11 . Moreover, to improve spatial resolution, we constructed a high-spatial resolution charge-coupled device ion-image sensor with a 128 × 128 pixel array 12 .…”

Formation and fluidity measurement of supported lipid bilayer on polyvinyl chloride membrane

“…[6][7][8][9] The component of the mixture solution for the fabrication of the plasticized PVC membrane is summarized in Table 1. It was slightly modified with the previous studies in refs.…”

“…An interdisciplinary example of the application of the ion-selective PVC membrane is the ion sensors based on field effect transistor (FET) 4,5 and charge-coupleddevice (CCD). [6][7][8][9] These ion sensors based on microelectronic devices measure the change of the surface potential of the sensing region due to the ion concentration in the solution as a shift in the drain current or voltage, and as a quantity of electric charges, respectively. The PVC membranes incorporating ionophores convert the ion concentration in the bulk solution to the surface potential change depending on the binding constant between the ionophore and its target ion.…”

Determination of Polyhexamethylene Biguanide Hydrochloride Using Photometric Colloidal Titration with Crystal Violet as a Color Indicator

“…14 However, the potentiometric method is inevitably accompanied by a reference electrode, which leaks a salt to a sample solution to some extent. 15 As a result, the leaked salt affects the stability constants of the colloidal titration reaction, which leads to titration errors. [8][9][10] Therefore, when conducting potentiometric colloidal titration, one should be careful in concerning the leakage of a salt from a reference electrode.…”