Recent Advances in Electrochemical Immunosensors

Piro, Benoı̂t; Reisberg, S.

doi:10.3390/s17040794

Cited by 78 publications

(45 citation statements)

References 191 publications

(249 reference statements)

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“…Globally, the use of immunosensors confers an important direction because of the benefits they offer as diagnostic devices. Immunosensors are easy to use, results are obtained in a short time, no sophisticated equipment or special working conditions are required, analytical performances are superior to current methods, and costs are low [ 49 ].…”

Section: Screen-printed Electrodes For Early Cancer Diagnosticmentioning

confidence: 99%

Screen-Printed Electrodes (SPE) for In Vitro Diagnostic Purpose

Mincu

Lazăr

Stan³

et al. 2020

Diagnostics

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Due to rapidly spreading infectious diseases and the high incidence of other diseases such as cancer or metabolic syndrome, there is a continuous need for the development of rapid and accurate diagnosis methods. Screen-printed electrodes-based biosensors have been reported to offer reliable results, with high sensitivity and selectivity and, in some cases, low detection limits. There are a series of materials (carbon, gold, platinum, etc.) used for the manufacturing of working electrodes. Each version comes with advantages, as well as challenges for their functionalization. Thus, the aim is to review the most promising biosensors developed using screen-printed electrodes for the detection/quantification of proteins, biomarkers, or pathogenic microorganisms.

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Section: Screen-printed Electrodes For Early Cancer Diagnosticmentioning

confidence: 99%

Screen-Printed Electrodes (SPE) for In Vitro Diagnostic Purpose

Mincu

Lazăr

Stan³

et al. 2020

Diagnostics

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“…The use of nanomaterials for signal amplification of immunosensors has allowed significant advances in the field of sensitive, portable and easy-to-use devices to detect biomarkers for clinical diagnosis or to monitor organic pollutants in the environment [ 272 ]. OMC materials have been exploited in the construction of several immunosensing devices [ 247 , 248 , 249 , 250 , 251 , 252 , 254 , 256 , 273 , 274 ] for the detection of specific antigens after binding to immobilized antibodies.…”

Section: Electrochemical Sensors and Biosensors Applicationsmentioning

confidence: 99%

Recent Trends on Electrochemical Sensors Based on Ordered Mesoporous Carbon

Walcarius

2017

Sensors

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The past decade has seen an increasing number of extensive studies devoted to the exploitation of ordered mesoporous carbon (OMC) materials in electrochemistry, notably in the fields of energy and sensing. The present review summarizes the recent achievements made in field of electroanalysis using electrodes modified with such nanomaterials. On the basis of comprehensive tables, the interest in OMC for designing electrochemical sensors is illustrated through the various applications developed to date. They include voltammetric detection after preconcentration, electrocatalysis (intrinsically due to OMC or based on suitable catalysts deposited onto OMC), electrochemical biosensors, as well as electrochemiluminescence and potentiometric sensors.

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“…All those characteristics make them ideal candidates to be implemented as screening tools. In the last three decades, several antibodies have been raised for the development of immunoassays for the detection of environmental pollutants either for Enzyme Linked Immunosorbent Assay (ELISA), lateral flow immunoassays or immunosensors [ 17 , 18 , 19 ]. On the other hand, the development of antibody-based techniques may be expensive and may require a long development.…”

Section: Introductionmentioning

confidence: 99%

Multiplexed Immunosensor Based on the Amperometric Transduction for Monitoring of Marine Pollutants in Sea Water

Salvador

Kopper

Miti

et al. 2020

Sensors

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Environmental pollutants vigilance is one of the main problems that the aquaculture industry has to face with the objective to ensure the quality of their products and prevent entrance in the food chain that finally may arrive to the consumer. Contaminants such as hormones, antibiotics or biocides are especially relevant due to their toxicity, pharmacological effect or hormonal activity that can be considered harmful for the final consumer. The contaminants can be detected in the environment where the food is growing, and their concentration can be found (i.e., seawater) in the range of µg·L−1, ng·L−1 or even in lower concentrations. Thus, sensitive and selective methods for their monitoring are required to avoid their arrival in the food chain. Here, the development of a multiplexed amperometric biosensor is described, based on the use of specific antibodies to reach the necessary detectability to measure the targeted contaminants directly in seawater. The multiplexed immunosensor allows the detection of four relevant pollutants, such as el Irgarol 1051, sulfapyridine, chloramphenicol and estradiol, reaching an IC50 of 5.04 ± 0.29, 3.45 ± 0.29, 4.17 ± 0.44 and 5.94 ± 0.28 µg·L−1, directly measured in seawater.

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Recent Advances in Electrochemical Immunosensors

Cited by 78 publications

References 191 publications

Screen-Printed Electrodes (SPE) for In Vitro Diagnostic Purpose

Screen-Printed Electrodes (SPE) for In Vitro Diagnostic Purpose

Recent Trends on Electrochemical Sensors Based on Ordered Mesoporous Carbon

Multiplexed Immunosensor Based on the Amperometric Transduction for Monitoring of Marine Pollutants in Sea Water

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