Recent Advances in Electrochemical Sensors Based on Molecularly Imprinted Polymers and Nanomaterials

Abstract

This review focuses on the recent achievement during period of 2013–2018 related to the electrochemical sensors based on molecularly imprinted polymers (MIPs) combined with nanomaterials for various kinds of applications. MIPs based electrochemical sensors have found a great interest due to their high stability, short time required for electropolymerization, and high specificity towards the target analyte. The sensitivity is considered as one of the important parameter in electrochemical sensing strategies that should be improved by the combination of highly conductive nanomaterials with selective MIPs. In general, the most employed nanomaterials are magnetic nanoparticles, gold nanoparticles (AuNPs), carbon nanotubes and graphene. This review discusses the main current achievement as well as the current challenges regarding the development of biomimetic sensors in electroanalysis.

A chitosan gold nanoparticles molecularly imprinted polymer based ciprofloxacin sensor

“…Molecular imprinting technique is also the substitute of natural receptors and successfully used as an articial analytical receptor for molecular identication with binding properties as natural antibodies in immunoassays. 10,11 Therefore, MIPs are termed as plastic anti-bodies. Literature reveals that including biological structure more than 10 000 molecules such as inorganic ions, drugs, cells, nucleic acid, protein, and viruses have been imprinted successfully.…”

MOLECULARLY IMPRINTED POLYMER NANOPARTICLES (MIP-NPs) APPLICATIONS IN ELECTROCHEMICAL SENSORS

“…When MIP-NP binds to the target analyte, the transducer will produce electrical signal depend on the concentration or number of target analytes that are bind to MIP-NP. Then, the signal was measured by the signal processor electrochemically, either through voltammetry, amperometry, potentiometry, or impedance [14,[36][37][38].…”

Molecularly Imprinted Polymers and Surface Imprinted Polymers Based Electrochemical Biosensor for Infectious Diseases

“…Several related reviews have been reported. Lahcen et al [10] mainly presented the development of MIPs modified with nanomaterials for electrochemical biosensors. Good electrical catalytic properties and excellent conductivity of nanomaterials combined with the comparable selectivity of MIPs endow them with powerful performance for various kinds of biomarkers.…”