Due to the development and application of information technology, a series of modern information technologies represented by 5G, big data, and artificial intelligence are changing rapidly, and people’s requirements for video coding standards have become higher. In the High-Efficiency Video Coding (HEVC) standard, the coding block division is not flexible enough, and the prediction mode is not detailed enough. A new generation of Versatile Video Coding (VVC) standards was born. VVC inherits the hybrid coding framework adopted by HEVC, improves the original technology of each module, introduces a series of new coding technologies, and builds on this greatly improving the coding efficiency. Compared with HEVC, the block division structure of VVC has undergone great changes, retaining the quad-tree (QT) division method and increasing the multi-type tree (MTT) division method, which brings high coding complexity. To reduce the computational complexity of VVC coding block division, a fast decision algorithm for VVC intra-frame coding based on texture characteristics and machine learning is proposed. First, we analyze the characteristics of the CU partition structure decision and then use the texture complexity of the CU partition structure decision to terminate the CU partition process early; for CUs that do not meet the early termination of the partition, use the global sample information, local sample information, and context information. The three-category feature-trained tandem classifier framework predicts the division type of CU. The experimental results show that in the full intra mode, compared with the existing VTM10.0, the encoding output bit rate is increased by 1.36%, and the encoding time is saved by 52.63%.