Recent advances in laser in situ keratomileusis‐associated dry eye

Xie, Wenjia

doi:10.1111/cxo.12361

Cited by 16 publications

(15 citation statements)

References 95 publications

(141 reference statements)

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“…Therefore, HD-OCT has the potential to become a routine eye evaluation method for DALK and other corneal surgeries. In our study, we found a significant negative correlation between age and CTFT in the fellow eye, which indicated that older age is a risk factor for tear film instability (Xie, 2016).…”

Section: Discussionsupporting

confidence: 61%

“…Dry eye is one of the common postoperative complications of corneal transplantation and may be associated with multiple mechanisms (Lin et al, 2014). During corneal-related surgery, the afferent nerve fibers of the cornea are severed, which may interrupt the cornea-trigeminal nerve-brainstem-facial nerve-lacrimal gland reflex arc and result in decreased tear secretion (Xie, 2016). The morphological changes of the transplanted cornea, such as corneal epithelium redistribution, the changed shape of the cornea and the sutures, may affect tear film distribution and increase tear evaporation.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Assessments of tear meniscus height, tear film thickness, and corneal epithelial thickness after deep anterior lamellar keratoplasty

Xie

Xia

et al. 2018

J. Zhejiang Univ. Sci. B

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Section: Discussionsupporting

confidence: 61%

Section: Introductionmentioning

confidence: 99%

Assessments of tear meniscus height, tear film thickness, and corneal epithelial thickness after deep anterior lamellar keratoplasty

Xie

Xia

et al. 2018

J. Zhejiang Univ. Sci. B

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“…Additionally, surgical incisions, conjunctival sutures and edema lead to morphological changes of ocular surface, which may also affect tear distribution and leading to decrease of tear film stability [27]. In this study, we found there were positive correlations between TMH and NITBUT-average at both 1 week and 2 weeks after PPV, demonstrating that surgery-induced reflex tearing also aggravates tear film destability.…”

Section: Discussionsupporting

confidence: 49%

Influence of Pars Plana Vitrectomy on Ocular Surface using Non-Invasive Keratograph 5M

Fan

Liu

Gao

et al. 2018

Preprint

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Background: The noninvasive Keratography has been used in evaluating surgery-induced ocular surface changes, while few were known about the influence of pars plana vitrectomy (PPV) on ocular surface. This study aimed to evaluate the influence of PPV on ocular surface using Keratograph 5M. Methods: 30 patients (30 eyes) undergoing primary PPV were recruited in the study. Ocular Surface Disease Index (OSDI) questionnaire was performed. Ocular surface parameters, including tear meniscus height (TMH), noninvasive tear break up time (NITBUT) and bulbar redness score were obtained preoperatively, at 1 week, 2 weeks, 4 weeks, 8 weeks and 12 weeks postoperatively by Keratograph 5M. Correlations between all the clinical parameters were analyzed further. Results: The percentages of both photophobia and gritty within 4 weeks after PPV were significantly higher than preoperation, while they decreased to the preoperative levels at both 8 weeks and 12 weeks postoperatively. The percentage of sore eyes within 2 weeks postoperatively was significantly higher than preoperation, but there were no significant differences between the percentages of preoperation and 4 weeks, 8 weeks and 12 weeks postoperatively. OSDI score increased significantly within 8 weeks postoperatively, but it returned to the preoperative level at 12 weeks. TMH was increased significantly at the first week after PPV, and recoverd to preoperative level at 2 weeks postoperatively. Both NITBUT-first and NITBUT-average shortened significantly within 8 weeks postoperatively, but they gradually improved to the preoperative levels at 12 weeks. Bulbar redness score was significantly higher than preoperative level within 4 weeks postoperatively, but it returned to the preoperative level at 8 weeks. NITBUT-first and NITBUT-average had a significant positive correlation at each visit. OSDI score had a significant positive correlation with bulbar redness, and TMH had a significant positive correlation with NITBUT-average at both 1 week and 2 weeks postoperatively. Conclusions: Keratograph 5M can provide a reliable noninvasive method to assess the influence of PPV on ocular surface. PPV may cause various changes in both symptoms and signs of ocular surface damages at an early stage, while all these changes will return to preoperative levels gradually at 12 weeks postoperatively.

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“…The validation of new methods for the diagnosis of incipient cases of KC or with mild visual loss is of great interest in the field of ophthalmology since there are several clinical treatments that would permit the end of further development of the disease [23]. For this reason, this work tries to perform a morphological analysis of the corneal structure's response to both the linear decompensation and the annular profile defined in the singular points of corneal surfaces.…”

Section: Discussionmentioning

confidence: 99%

Study of Morpho-Geometric Variables to Improve the Diagnosis in Keratoconus with Mild Visual Limitation

et al. 2018

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The validation of new methods for the diagnosis of incipient cases of Keratoconus (KC) with mild visual limitation is of great interest in the field of ophthalmology. During the asymmetric progression of the disease, the current diagnostic indexes do not record the geometric decompensation of the corneal curvature nor the variation of the spatial profile that occurs in singular points of the cornea. The purpose of this work is to determine the structural characterization of the asymmetry of the disease by using morpho-geometric parameters in KC eyes with mild visual limitation including using an analysis of a patient-specific virtual model with the aid of computer-aided design (CAD) tools. This comparative study included 80 eyes of patients classified as mild KC according to the degree of visual limitation and a control group of 122 eyes of normal patients. The metric with the highest area under the receiver operating characteristic (ROC) curve was the posterior apex deviation. The most prominent correlation was found between the anterior and posterior deviations of the thinnest point for the mild keratoconic cases. This new custom computational approach provides the clinician with a three-dimensional view of the corneal architecture when the visual loss starts to impair.

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Recent advances in laser in situ keratomileusis‐associated dry eye

Cited by 16 publications

References 95 publications

Assessments of tear meniscus height, tear film thickness, and corneal epithelial thickness after deep anterior lamellar keratoplasty

Assessments of tear meniscus height, tear film thickness, and corneal epithelial thickness after deep anterior lamellar keratoplasty

Influence of Pars Plana Vitrectomy on Ocular Surface using Non-Invasive Keratograph 5M

Study of Morpho-Geometric Variables to Improve the Diagnosis in Keratoconus with Mild Visual Limitation

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