Recent advances in medicinal and edible homologous plant polysaccharides: Preparation, structure and prevention and treatment of diabetes

Li, Lan; Xie, Jingchen; Zhang, Zhimin; Xia, Bohou; Li, Yamei; Lin, Yan; Li, Minjie; Wu, Ping; Lin, Limei

doi:10.1016/j.ijbiomac.2023.128873

Cited by 10 publications

(1 citation statement)

References 173 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Different extraction methods result in changes in the physicochemical attributes and structure of polysaccharides—mainly in their yield, total sugar content, uronic acid content, M w , monosaccharide composition, surface topography, and thermal stability [ 16 ]. Ultrasound-assisted extraction uses the cavitation effect caused by ultrasound to destroy the plant cell wall and promote the rapid entry of solvent into the cell interior to achieve rapid and efficient extraction [ 17 ]. Ultrasonic degradation is a good physical method for the production of polysaccharides with a low value of M w , in which a break in the glycoside bond of the main chain of the polysaccharide occurs [ 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Study of the Structure and Bioactivity of Polysaccharides from Different Parts of Stemona tuberosa Lour

Qiu,

Ou,

et al. 2024

Molecules

View full text Add to dashboard Cite

The polysaccharides from Stemona tuberosa Lour, a kind of plant used in Chinese herbal medicine, have various pharmacological activities, such as anti-inflammatory and antioxidant properties. However, the effects of the extraction methods and the activity of polysaccharides from different parts are still unknown. Therefore, this study aimed to evaluate the effects of different extraction methods on the yields, chemical compositions, and bioactivity of polysaccharides extracted from different parts of Stemona tuberosa Lour. Six polysaccharides were extracted from the leaves, roots, and stems of Stemona tuberosa Lour through the use of hot water (i.e., SPS-L1, SPS-R1, and SPS-S1) and an ultrasound-assisted method (i.e., SPS-L2, SPS-R2, and SPS-S2). The results showed that the physicochemical properties, structural properties, and biological activity of the polysaccharides varied with the extraction methods and parts. SPS-R1 and SPS-R2 had higher extraction yields and total sugar contents than those of the other SPSs (SPS-L1, SPS-L2, SPS-S1, and SPS-S2). SPS-L1 had favorable antioxidant activity and the ability to downregulate MUC5AC expression. An investigation of the anti-inflammatory properties showed that SPS-R1 and SPS-R2 had greater anti-inflammatory activities, while SPS-R2 demonstrated the strongest anti-inflammatory potential. The results of this study indicated that SPS-L1 and SPS-L2, which were extracted from non-medicinal parts, may serve as potent natural antioxidants, but further study is necessary to explore their potential applications in the treatment of diseases. The positive anti-inflammatory effects of SPS-R1 and SPS-R2 in the roots may be further exploited in drugs for the treatment of inflammation.

show abstract

Section: Introductionmentioning

confidence: 99%

Study of the Structure and Bioactivity of Polysaccharides from Different Parts of Stemona tuberosa Lour

Qiu,

Ou,

et al. 2024

Molecules

View full text Add to dashboard Cite

show abstract

Insights Into Metabolic Signatures and Regulatory Effect of Dendrobium officinale Polysaccharides in Gut Microbiota: A Comparative Study of Healthy and Diabetic Status

Song,

Zou,

Cheng

et al. 2024

Food Science & Nutrition

View full text Add to dashboard Cite

Dendrobium officinale is a kind of popular functional food to be consumed by both healthy and diabetic people. As its major constituent, D. officinale polysaccharide (DOP) is mainly utilized by gut microbiota. Despite distinctive gut microbiota composition between healthy and diabetic individuals, no study compared the interplay between DOP and gut microbiota under healthy and diabetic status. The current study aims to investigate and compare the metabolic signatures and regulatory potential of DOP on gut microbiota between healthy and diabetic status. Our serial in vitro fermentation investigations found that mannose in DOP was more utilized by gut microbiota under diabetic status with higher production of propanoic acid and lower production of butyric acid compared with those under healthy status. Moreover, metabolomic analyses revealed different impacts of DOP on intestinal microbial metabolites between healthy and diabetic status with upregulating taurine and downregulating 2‐hydroxybutyric acid only occurring under diabetic status. Biodiversity analyses demonstrated that DOP treatment could only significantly improve the diversity of gut microbiota under diabetic status while there was no significant effect on that under healthy status. Further gut microbiota composition analyses indicated that DOP treatment could promote probiotics (Dubosiella, Bifidobacterium, and Akkermansia) under both healthy and diabetic status while inhibit pathogens (Escherichia‐Shigella) only under diabetic status. In summary, our current insights into metabolic signatures and regulatory effects of DOP in the gut microbiota under healthy and diabetic status provided scientific evidence for its broad use as functional food.

show abstract

Extraction, purification, structural characteristics and biological properties of the polysaccharides from Armillaria mellea (Vahl) P. Kumm.: A review

Chen,

Liu,

Ren

et al. 2024

International Journal of Biological Macromolecules

View full text Add to dashboard Cite

Recent advances in medicinal and edible homologous plant polysaccharides: Preparation, structure and prevention and treatment of diabetes

Cited by 10 publications

References 173 publications

Study of the Structure and Bioactivity of Polysaccharides from Different Parts of Stemona tuberosa Lour

Study of the Structure and Bioactivity of Polysaccharides from Different Parts of Stemona tuberosa Lour

Insights Into Metabolic Signatures and Regulatory Effect of Dendrobium officinale Polysaccharides in Gut Microbiota: A Comparative Study of Healthy and Diabetic Status

Extraction, purification, structural characteristics and biological properties of the polysaccharides from Armillaria mellea (Vahl) P. Kumm.: A review

Contact Info

Product

Resources

About