Recent Advances in Modifications, Properties and Applications of 2-Isopropyl-2-Oxazoline (Co)Polymers

Amino-modified 2-oxazoline copolymers for complexation with DNA

“…In the last decade, there has been great progress in the reported potential use of poly(2-substituted-2-oxazoline)s (POxs) in biomedical areas, as they are often considered as PEG alternatives for biomedical purposes. [22][23][24][25] Due to the fact that these polymers possess in their structure various nitrogen containing groups, they have been used for the preparation of polyplexes. POxs applied to build polyplexes usually contain amino groups generated within the main chain, or introduced into the substituents.…”

Chelate-functionalized poly(2-oxazoline) for the destruction of bacterial cell membranes

“…Poly(2-oxazoline)s are non-toxic, relatively easy to obtain and modify, and widely applied in biology and medicine. [30][31][32][33][34][35][36][37] Considering antibacterial systems, in recent years, the use of poly(2-oxazoline)s carrying quaternized nitrogen 38 or complexed with metal ions 39 has been indicated. In the proposed antibacterial system, the copolymer of 2-ethyl-2oxazoline (EtOx) and 2-(3-butenyl)-2-oxazoline (ButEnOx) was conjugated with a polyamino polycarboxylic bifunctional chelating agent (BFCA).…”

Synthesis and solution properties of telechelic poly(2-isopropyl-2-oxazoline) bearing perfluoro end groups

“…[3][4][5] TEM, optical microscopy, IR, NMR, light scattering, XRD, and other techniques have been used to investigate the phase separation process of PIPOZ in hot water. 3,[6][7][8][9][10][11] A liquid-liquid phase separation followed by the crystallization mechanism of this process has been broadly accepted, which involves the conformational change of the backbone and packing of the PIPOZ chains through dipolar and hydrophobic interactions. 7,9,[12][13][14][15] The effect of hydrophobic end group modification on the T c of PIPOZ has been examined.…”