Recent advances in non-optical microfluidic platforms for bioparticle detection

Bayinqiaoge,; Zhang, Yuxin; Cole, Tim; Zheng, Jiahao; Guo, Jinhong; Tang, Shi‐Yang

doi:10.1016/j.bios.2022.114944

Cited by 9 publications

(4 citation statements)

References 133 publications

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“…Microfluidics, a technique for manipulating fluids in microchannels at the micron level, has set the trend for engineering improvements in areas such as flow cytometry, 21 microscale chemical synthesis, 22 bioparticle detection, 23 and cell culture. 24 Particularly due to the rapid development of ML in recent decades, which has greatly enhanced the ability of microfluidic platforms to process data, the construction of intelligent microfluidic platforms resulting from the combination of these two disciplines has received increasing attention.…”

Section: Introductionmentioning

confidence: 99%

An automated and intelligent microfluidic platform for microalgae detection and monitoring

Zheng,

Cole,

Zhang

et al. 2024

Lab Chip

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Section: Introductionmentioning

confidence: 99%

An automated and intelligent microfluidic platform for microalgae detection and monitoring

Zheng,

Cole,

Zhang

et al. 2024

Lab Chip

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“…In this sense, although on-chip optical detection techniques have proven their value in several applications, such as in the development of point-of-care diagnostics [ 32 ], and miniaturized/portable equipment based on classical microscopy and many UV–vis–NIR techniques are commercially available, in other cases the high price of optical components and the requirement of particular bulky devices for technique implementation have limited their practicality in the development of “truly portable” tools for field applications. At the same time, non-optical detection schemes based on electronics (such as electrical, magnetic, and acoustic detection-based devices, which have been the subject of a recent review [ 33 ]), while they can be cost-effective and more easily integrated taking advantage of microelectronics developments, can also require the coupling of side and frequently bulky materials and equipment for detection [ 33 ].…”

Section: Introductionmentioning

confidence: 99%

On-Chip Photonic Detection Techniques for Non-Invasive In Situ Characterizations at the Microfluidic Scale

Kurdadze,

Lamadie,

Nehme

et al. 2024

Sensors

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Microfluidics has emerged as a robust technology for diverse applications, ranging from bio-medical diagnostics to chemical analysis. Among the different characterization techniques that can be used to analyze samples at the microfluidic scale, the coupling of photonic detection techniques and on-chip configurations is particularly advantageous due to its non-invasive nature, which permits sensitive, real-time, high throughput, and rapid analyses, taking advantage of the microfluidic special environments and reduced sample volumes. Putting a special emphasis on integrated detection schemes, this review article explores the most relevant advances in the on-chip implementation of UV–vis, near-infrared, terahertz, and X-ray-based techniques for different characterizations, ranging from punctual spectroscopic or scattering-based measurements to different types of mapping/imaging. The principles of the techniques and their interest are discussed through their application to different systems.

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“…In addition, magnetic systems are easy to integrate and require a relatively low detection environment. 16…”

Section: Introductionmentioning

confidence: 99%

“…In addition, magnetic systems are easy to integrate and require a relatively low detection environment. 16 The main structures synthesized by MNPs are core/shell structures, among which gold magnetic nanoparticles (GMNPs) have remarkably high stability and currently show great potential for development in various fields. Liu et al used GMNPs in their amplification refractory mutation system (ARMS), which can test multiple single nucleotide polymorphisms (SNPs), and the results demonstrate the advantages of high sensitivity and specificity.…”

Section: Introductionmentioning

confidence: 99%