Recent Advances in Plant Metabolomics: From Metabolic Pathways to Health Impact

Figueiredo, Andreia; Hugueney, Philippe; Durazzo, Alessandra

doi:10.3390/biology11020238

Cited by 6 publications

(1 citation statement)

References 9 publications

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“…In recent years, plant extracts have attracted great interest for the potential large-scale application of AIs. A wide range of biologically active compounds endowed with several functions and properties [ 51 , 52 ] can be synthesized at various concentrations in all plant organs or parts—i.e., leaves, flowers, fruits, roots, barks, tubers, rhizomes—and there is an ever-growing effort to take advantage of the nutraceutical features of natural products [ 53 , 54 , 55 ].…”

Section: Active Ingredientsmentioning

confidence: 99%

Natural Active Ingredients for Poly (Lactic Acid)-Based Materials: State of the Art and Perspectives

et al. 2022

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This review describes the state of the art in the field of poly (lactic acid) (PLA)-based materials activated by natural compounds and extracts (active ingredients, AIs) from plant sources for food and biomedical applications. With a multidisciplinary approach, after a description of the synthesis and properties of PLA, special attention was paid to the chemical properties and unconventional extraction technologies of AIs used for PLA activation. Innovative techniques for the incorporation of AIs into PLA; characterization and the antioxidant and antimicrobial properties of the novel materials were discussed. In view of future perspectives, this study has evidenced that some aspects need to be further investigated from joint research between academia and industry, according to the green chemistry principles and circular economy strategy.

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Section: Active Ingredientsmentioning

confidence: 99%

Natural Active Ingredients for Poly (Lactic Acid)-Based Materials: State of the Art and Perspectives

et al. 2022

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Diterpenes and triterpenes show potential as biocides against pathogenic fungi and oomycetes: a screening study

Adamczyk,

Latvala,

Poimala

et al. 2023

Biotechnol Lett

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Objectives The aim was to screen di- and triterpenes as potential biocides against fungal pathogens (Alternaria sp., Fusarium avenaceum, F. sambucinum, Botrytis cinerea, Botryotina fuckeliana, Mycocentrospora acerina, Cylindrocarpon sp.) and oomycetes (Phytophthora cactorum, P. fragariae). Results We measured the antifungal activity of terpenes by estimating the growth area, ergosterol content and level of lipid peroxidation. Fungi and oomycetes were grown on solid media in Petri dishes. As a positive control, we used a common synthetic fungicide, fosetyl-Al. Di- and triterpenes showed promising potential as biocides against most of the studied species. The responses of fungi and oomycetes were dependent on the specific type of terpenes and identity of the fungi. Compared to synthetic fungicide, terpenes were equally effective as antifungal agents and even more effective for some species, especially for oomycetes. The terpene mode of action includes inhibition of ergosterol synthesis and increased lipid peroxidation. Conclusions Di- and triterpenes, natural compounds that are very abundant in northern countries, are excellent candidates for biocides.

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Production and Characterization of a β-Cyclodextrin Inclusion Complex with Platonia insignis Seed Extract as a Proposal for a Gastroprotective System

et al. 2022

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Platonia insignis Mart, Clusiaceae, known as bacuri, is a species native to Brazil that, in studies with extract of the seed of its fruit, showed antioxidant activity against free radicals. Products with such properties may be of great importance in the treatment of peptic ulcers since this pathology may be associated with the inflammatory process caused by the action of free radicals. Cyclodextrins are molecules capable of forming inclusion complexes with other molecules, affecting their physicochemical properties and improving their pharmacokinetic characteristics. Thus, this work aimed to produce, characterize, and evaluate the gastroprotective effect of the inclusion complex of β-cyclodextrin (β-CD) with the bacuri seeds hexanic extract (BSHE). In the characterization of the inclusion complex, an apparent stability constant (Kc) of 416 mol/L was obtained in the solubility study; the BSHE:β-CD m/m (g) complexation ratios at 1:9, 2:8, and 3:7 were 5.51%, 21.46%, and 20.11%, respectively. The formation of the BSHE:β-CD inclusion complex was observed by FTIR technique, indicating the disappearance of bands characteristic of BSHE (2960 cm−1 and 1755 cm−1) when in the complex, compared to the spectra of pure BSHE or in physical mixture with β-CD, and by X-ray diffraction, which indicated a loss of crystallinity, typical signals of pure β-CD, and presentation of intense amorphization, characteristic of BSHE, incorporated in the β-CD pockets. In the evaluation of gastroprotective activity, through absolute ethanol-induced gastric lesions in mice, both BSHE and BSHE:β-CD reduced gastric lesions, with 100 mg/kg dose of the complex having the greatest gastroprotective effect. BSHE:β-CD was also able to reduce gastric lesions from ischemia and reperfusion, with the 50 mg/kg dose being the most effective. BSHE:β-CD, also at this dose, reduced the MDA levels of the gastric mucosa, indicating a possible antioxidant activity in its gastroprotective effect. Thus, it was concluded that inclusion complex formation between β-CD and BSHE is possible, and that this formulation enhanced the gastric protective activity.

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Recent Advances in Plant Metabolomics: From Metabolic Pathways to Health Impact

Abstract: In the past decade, technological development allowed a rapid advance on several OMIC approaches, metabolomics was no exception. [...]

Cited by 6 publications

References 9 publications

Natural Active Ingredients for Poly (Lactic Acid)-Based Materials: State of the Art and Perspectives

Natural Active Ingredients for Poly (Lactic Acid)-Based Materials: State of the Art and Perspectives

Diterpenes and triterpenes show potential as biocides against pathogenic fungi and oomycetes: a screening study

Production and Characterization of a β-Cyclodextrin Inclusion Complex with Platonia insignis Seed Extract as a Proposal for a Gastroprotective System

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