A micro direct methanol fuel cell (μDMFC) is suitable for use in notebook computers, mobile phones, and other digital products. To resolve the poor mass-transport efficiency problem in the anode flow channel, this paper presents an N-inputs-N-outputs parallel flow pattern with rectangular convexes to reinforce methanol mass transport and reduce concentration polarization. The simulation results show that the N-inputs-N-outputs parallel flow channels with the rectangle convexes improve the performance. μDMFCs, which have four anode flow patterns, are fabricated using MEMS (microelectromechanical systems) technology. The experimental results show that the μDMFC with the rectangle convexes has a performance better than previously reported systems, and has a peak power density of 19.96 mW/cm 2 . The simulation and experimental results are in good agreement.