Recent Lipid Membrane-Based Biosensing Platforms

Abstract

The investigation of lipid films for the construction of biosensors has recently given the opportunity to manufacture devices to selectively detect a wide range of food toxicants, environmental pollutants, and compounds of clinical interest. Biosensor miniaturization using nanotechnological tools has provided novel routes to immobilize various “receptors” within the lipid film. This chapter reviews and exploits platforms in biosensors based on lipid membrane technology that are used in food, environmental, and clinical chemistry to detect various toxicants. Examples of applications are described with an emphasis on novel systems, new sensing techniques, and nanotechnology-based transduction schemes. The compounds that can be monitored are insecticides, pesticides, herbicides, metals, toxins, antibiotics, microorganisms, hormones, dioxins, etc.

The Emergence of Insect Odorant Receptor-Based Biosensors

“…The incorporation of ion channels is generally preferable in biosensing since they allow for low detection limits. Controlling the orientation of OR within the SLB, however, is still considered a challenge [80].…”

Biologically interfaced nanoplasmonic sensors

“…17,18 However, recent works have also demonstrated the possibility of directly introducing a biological interface without any surface modication. 19,20 In this review, we discuss recent progress in the development of biologically interfaced nanoplasmonic sensors with emphasis on the latest strategies employed for surface modication and biological functionalization. We begin by describing the processes involved in the design and fabrication of nanoplasmonic architectures within the context of biological-related applications, highlighting notable design features that have been adopted to facilitate biological interfacing.…”

Nanotechnological advances of Lipid film-based biosensors for the rapid detection of biological compounds and toxicants

“…Figure 1 shows the function and composition of a biosensor based on lipid film technology, illustrating, also, the physicochemical mechanism for the electrochemical transduction and the most common screening strategies employed. A number of recent articles have appeared in the literature that mainly describe recent advances and applications of various platforms of lipid film-based biosensors [6,[10][11][12][13][14].…”