Recent Literature on Medication Errors and Adverse Drug Events in Older Adults

Naples, Jennifer G.; Hanlon, Joseph T.; Schmader, Kenneth E.; Semla, Todd P.

doi:10.1111/jgs.13922

Cited by 24 publications

(19 citation statements)

References 35 publications

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“…The term ‘deprescribing’ has since gained wide acceptance, and over recent years there has been an explosion of research focussing on deprescribing, along with the development of guidelines to support physicians and pharmacists to deprescribe . Citing the 2003 article, it was recently stated in the Journal of the American Geriatrics Society that ‘ Deprescribing is an increasingly important concept that may enable providers to avoid the clinical inertia that leads to persistent use of potentially inappropriate medications .’…”

Section: Early Articles and Changes In Therapeutics Over The Last 30 mentioning

confidence: 99%

“…39 Citing the 2003 article, it was recently stated in the Journal of the American Geriatrics Society that 'Deprescribing is an increasingly important concept that may enable providers to avoid the clinical inertia that leads to persistent use of potentially inappropriate medications.' 40 Building on that seminal 2003 article, over the next 10 years several Geriatric Therapeutics articles related to deprescribing were published. These addressed identifying potentially inappropriate medications, ethical issues associated with prescribing for the elderly, and end of life prescribing.…”

Section: Improving Medication Outcomes For Older Peoplementioning

confidence: 99%

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Thirty years of Geriatric Therapeutics

Elliott

Woodward

2016

Pharmacy Practice and Res

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In the 1980s geriatric medicine was in its infancy in Australia, and geriatric therapeutics was a newly developing field. There was little primary literature regarding geriatric pharmacology and pharmacotherapy in older people. The Heidelberg Repatriation Hospital in Melbourne appointed its first geriatrician in 1983, and the ‘Geriatric Therapeutics’ series of articles (now known as ‘Geriatric Therapeutics Review’) began in 1986, as a partnership between the hospital's Pharmacy and Aged and Extended Care departments. Until 1990 Geriatric Therapeutics articles were published in the hospital's Pharmacy Bulletin. Since 1991 they have been published in this journal. For 30 years the series has provided readers with contemporary reviews of the management of medical problems in older people, with an emphasis on rational and safe drug therapy. Over that period there have been considerable changes in the therapeutic management of diseases that commonly affect older people, and the 125 articles published between 1986 and 2016 reflect many of those changes. To commemorate the 30th Anniversary of the Geriatric Therapeutics series, this article describes its origins and development, and some of the changes in therapeutics that have occurred over the last 30 years.

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Section: Early Articles and Changes In Therapeutics Over The Last 30 mentioning

confidence: 99%

Section: Improving Medication Outcomes For Older Peoplementioning

confidence: 99%

Thirty years of Geriatric Therapeutics

Elliott

Woodward

2016

Pharmacy Practice and Res

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“…1 Ever since the consequences of medication errors have been described in landmark report "To Err Is Human", 2 this topic has been prioritized by World Health Organization (WHO) 3 and numerous policy documents and research studies have been published highlighting growing concerns about the frequency and impact of medication errors. [4][5][6][7] Dispensing of medicines traditionally represents one of the main pharmacists' activities in the provision of health care. 8 However, this process is highly complex and consists of a number of steps that have to be performed before the medicine is issued to the patient.…”

Section: Introductionmentioning

confidence: 99%

Community Pharmacists’ Attitudes and Professional Practice in Relation to the Patient Safety Incidents

Marinković¹,

Stojković²,

Zeković³

et al. 2019

IJPER

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Background: Medicines dispensing is an error-prone activity, therefore potentially jeopardizing patient safety. This study aimed to assess the community pharmacists' attitudes towards the causes of dispensing errors and preventive measures, as well as their practice in incidents reporting. Materials and Methods: A cross-sectional survey was performed by distributing an adopted and validated questionnaire to a nationwide sample of community pharmacists in Serbia. The questionnaire included sections related to the participants' socio-demographic characteristics, their attitudes towards factors causing dispensing errors and corrective actions, as well as their practice in reporting. Statistical analyses were conducted using SPSS Statistics software ver. 21.0. The associations between categorical variables were analyzed using Chi-square test. Results: The study included 1,004 participants, mainly female (94.9%), with the mean age 40.9±9.9 years and mean work experience 14.3±10.0 years. More than a third of the participants (35.4%) indicated an increasing risk of dispensing errors. The main causes included illegible prescriber's handwriting (44.3%) and interruptions during dispensing (39.2%), while the major corrective actions were providing pharmacists with education in clinical pharmacy (71%) and reducing the interruptions during dispensing (63.9%). The majority of respondents (85.2%) stated that they routinely reported dispensing incidents. However, even 16.5% of them admitted to having fear sometimes or always. Additionally, only 58.1% of participants would use voluntary dispensing error reporting system. Conclusion: Serbian community pharmacists are aware of the existing risk in medicines dispensing and the corrective actions identified should be put into practice so as to manage them prospectively. Although the results indicate good practice in incidents reporting, conducting tailored educations and building of safety culture is necessary to improve patient safety.

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“…According to pharmaceutical care network of Europe (PCNE), DRP is defined as, "an event or circumstance involving drug therapy that actually or potentially interferes with desired health outcomes" [6]. DRPs are associated with increased healthcare costs and hospital admissions, prolonged hospital stays, reduced quality of life, and increased mortality [7,8]. Therefore, drug prescribing and use in older patients needs special considerations including avoidance of inappropriate drugs, rational utilization of indicated medications, side effects monitoring, prevention of drug-drug interactions, and evaluation of adherence and patient involvements [9].…”

Section: Introductionmentioning

confidence: 99%

Drug related problems in admitted geriatric patients: The impact of clinical pharmacist interventions

Hailu

Berhe

Gudina

et al. 2019

Preprint

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Background: Geriatric patients are at high risk of Drug Related Problems (DRPs) due to multi- morbidity associated polypharmacy, age related physiologic changes, pharmacokinetic and pharmacodynamics alterations. These patients are often excluded from premarketing trials that can further increase the occurrence of DRPs. This study was aimed to identify DRPs and determinants in geriatric patients admitted to medical and surgical wards, and to evaluate the impact of clinical pharmacist interventions for treatment optimization. Methods: A prospective observational study was conducted among geriatric patients admitted to medical and surgical wards of Jimma University Medical Center from April to July 2017. Clinical pharmacists reviewed patients drug therapy, identified drug related problems and provided interventions. Data were analyzed by using SPSS statistical software version 20.0. Descriptive statistics were performed to determine the proportion of drug related problems. Logistic regression analyses were performed to identify the determinants of drug related problems. Results: A total of 200 geriatric patients were included in the study. The mean age of the participants was 67.3 years (SD7.3). About 82% of the patients had at least one drug related problems. A total of 380 drug related problems were identified and 670 interventions were provided. For the clinical pharmacist interventions, the prescriber acceptance rate was 91.7%. Significant determinants for drug related problems were polypharmacy (adjusted odds ratio [AOR]=4.350, 95% C.I: 1.212-9.260, p = 0.020) and number of comorbidities (AOR=1.588, 95% C.I: 1.029-2.450, p = 0.037). Conclusions: Drug related problems were substantially high among geriatric inpatients. Geriatric patients with polypharmacy and comorbidities need special attention to prevent drug related problems. Involving clinical pharmacist in the clinical team resulted in the improved acceptance rate of treatment optimization.

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Recent Literature on Medication Errors and Adverse Drug Events in Older Adults

Cited by 24 publications

References 35 publications

Thirty years of Geriatric Therapeutics

Thirty years of Geriatric Therapeutics

Community Pharmacists’ Attitudes and Professional Practice in Relation to the Patient Safety Incidents

Drug related problems in admitted geriatric patients: The impact of clinical pharmacist interventions

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