Recent progress in nanotechnology-based drug carriers for resveratrol delivery

Li, Chunhong; Wang, Zhen; Lei, Hui; Zhang, Dan

doi:10.1080/10717544.2023.2174206

Cited by 51 publications

(28 citation statements)

References 156 publications

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“…They proficiently ferry various active substances into cells, including siRNA, miRNA, and peptides. 67 In a study conducted by Yao et al, CGA was loaded onto tFNA NPs, resulting in the synthesis of tFNAs-CGA (Fig. 4A).…”

Section: Nanoparticle Delivery Systemsmentioning

confidence: 99%

Unleashing the power of chlorogenic acid: exploring its potential in nutrition delivery and the food industry

Hu,

Zhao,

Chi

et al. 2024

Food Funct.

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Section: Nanoparticle Delivery Systemsmentioning

confidence: 99%

Unleashing the power of chlorogenic acid: exploring its potential in nutrition delivery and the food industry

Hu,

Zhao,

Chi

et al. 2024

Food Funct.

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“…Based on the results obtained by in vitro and in vivo studies, high doses of resveratrol are likely required to achieve potential health benefits. Determination of the most effective formulation and dosage remains an area of ongoing research (Li et al., 2023).…”

Section: Pros and Cons Of Resveratrolmentioning

confidence: 99%

Certainty and uncertainty in the biological activities of resveratrol

Drago,

Ciprandi,

Brindisi

et al. 2024

Food Frontiers

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Resveratrol is a nonflavonoid polyphenolic compound with a chemical structure consisting of two aromatic rings linked by a methylene bridge. It exists in two primary isomers and has a broad range of desirable biological activities, including antioxidant, anti‐inflammatory, antidiabetic, cardioprotective, and antitumor activities. Some antioxidant properties of resveratrol are known with certainty, such as its potential to positively impact cardiovascular health, inflammation, and the metabolism. On the other hand, many uncertainties and controversies plague its efficacy, including issues related to its bioavailability, dosing, human clinical trial results, interactions with other food components and drugs, and individual variability. In brief, although promising results have been observed in in vitro and in vivo studies, the translation of these findings to human health remains uncertain. Many human clinical trials on resveratrol are ongoing or have proven inconclusive, making it challenging to definitively determine its efficacy for specific health conditions and its dose and duration of treatment. Resveratrol may interact with medications and have varying effects on individuals. In conclusion, it is essential to approach resveratrol with a balanced perspective, consulting with healthcare professionals, and considering the evolving scientific evidence when making decisions regarding its clinical use.

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“…Resveratrol, a bioactive polyphenol secreted by at least 100 different plants, has a number of functional properties, including antioxidant, anti-inflammatory, platelet aggregation and activation inhibition, antiaging, and antidiabetic properties [59]. Qi et al [60] first prepared a polysulfone/resveratrol blend membrane using an immersion precipitation phase inversion method.…”

Section: State-of-the-art Laboratory Investigations Of Ahmsmentioning

confidence: 99%

Alleviation of Oxidative Stress during Hemodialysis Sessions by Hemodialysis Membrane Innovation: A Multidisciplinary Perspective

Li,

Luo,

Yang

et al. 2023

Blood Purif

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Oxidative stress is prevalent in end-stage kidney disease patients receiving chronic hemodialysis and is associated with heavy cardiovascular disease burdens and increased mortality risks. Hemoincompatible hemodialysis membranes per se contribute to the activation of oxidative reactions and the generation of oxygen free radicals. Since the early 1990s, vitamin E-coated membranes have been extensively used in hemodialysis patients to reduce oxidative stress during hemodialysis sessions. However, the beneficial effects of vitamin E-coated membranes versus unmodified synthetic membranes on long-term patient-centered outcomes, such as survival, quality of life, and prevalence of cardiovascular diseases, remain controversial. Accordingly, novel antioxidant hemodialysis membranes were prepared to replace the use of vitamin E-coated membranes despite the translational research on these membranes unfortunately coming to a standstill. In this review, we first summarize the state-of-the-art on the use of vitamin E-coated membranes in hemodialysis patients to highlight their strengths and limitations. Then, we discuss the latest advances in fabricating antioxidant hemodialysis membranes and provide perspectives to bridge knowledge gaps between laboratorial investigations and clinical practice in fabricating antioxidant hemodialysis membranes.

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Recent progress in nanotechnology-based drug carriers for resveratrol delivery

Cited by 51 publications

References 156 publications

Unleashing the power of chlorogenic acid: exploring its potential in nutrition delivery and the food industry

Unleashing the power of chlorogenic acid: exploring its potential in nutrition delivery and the food industry

Certainty and uncertainty in the biological activities of resveratrol

Alleviation of Oxidative Stress during Hemodialysis Sessions by Hemodialysis Membrane Innovation: A Multidisciplinary Perspective

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