Recent progress in nanozyme-based sensors for ion detection: strategies, trends, and challenges

Abstract

In-situ real-time monitoring of pollution sources is one of the most effective means to control and prevent toxic ions from harming the environment and human health. To this end, it...

Nanozymes: powerful catalytic materials for environmental pollutant detection and degradation

“…This makes nanozymes find intensive use in biochemical and environmental analyses. [22][23][24] Currently, there are mainly four principles established for target detection with the participation of nanozymes (Fig. 2): (1) some analytes take part in nanozyme-catalyzed reactions as substrates, offering a direct approach to detect these species; (2) the catalytic activity of nanozymes can be regulated by specific molecules and ions, and this provides a common principle to sense these targets; (3) instead of directly interacting with nanozymes, many analytes have impacts on nanozymecatalyzed systems via competitive reactions or combining with reactants or products, also enabling the development of sensors for analyte monitoring; (4) naturally, nanozymes employed as an alternative to natural enzymes can be integrated with other sensing units (antibodies, enzymes, aptamers, etc.)…”

Deep eutectic solvent-assisted synthesis of La–Ce hybrid nanorods for the colorimetric determination of tetracycline in foods

“…[23][24][25] Colorimetric assays based on mimetic enzymes have garnered a lot of attention in recent years, [26][27][28] and the application of peroxidase activity of nanozymes to perform colorimetric assays in TC has also been studied. [29][30][31] Chen et al synthesized a trinuclear MOF of NiCoFe with a hollow structure, which has strong uorescence and good peroxidase activity. This MOF structure was used to construct a dual-signal output biosensor, and the biosensor was used for the determination of TC in honey.…”

Enhancing Nanozyme-Based Colorimetric Assays by Optimizing Substrate Composition

“…We therefore consider that optimization of substrate solution is cost-effective, simple, and efficient way to increase sensitivity of nanozyme-based assays. Moreover, there is a growing number of colorimetric sensors of ions and small molecules based on their ability to modulate catalytic activity of nanozymes (Behera and De, 2024;Li et al, 2023).…”