Recent Progress of Visible Light-Induced the Synthesis of C(3) (Hetero)arylthio Indole Compounds

Abstract

The structure of 3-sulfenyl indoles widely exists in many drug molecules and natural product molecules. Its derivatives have extensive biological activities such as antibacterial, antiviral and anti-tumor, and are also important intermediates of organic synthesis and structural units of drug synthesis. Therefore, 3-sulfenyl indole compounds have great application value in the field of medicine. The research of its synthesis method has also become one of the current research hotspots. In this paper, the research progress in the synthesis of 3-sulfenyl indoles compounds in recent years is reviewed, and some reaction mechanisms are also discussed. Keywords 3-sulfenyl indole; photocatalysis; C-S bond formation; synthesis REVIEW