Recent Therapeutics

Absorption of Folic Acid and D-Xylose as Tests of Small-intestinal Function

“…Butterworth, Perez-Santiago, Martinez de Jesus, and Santini (1959) found that in normal subjects 80% of the xylose appearing in the urine was excreted in the first five hours, whereas in five patients with untreated sprue only 55% of the material appearing in the urine was excreted in the same period. A similar observation was made by Fourman (1948). The delayed urinary excretion of xyjose in sprue was confirmed by giving xylose intravenously.…”

Diagnostic Significance of d.Xylose Excretion Test

“…In particular, its use in conditions associated with steatorrhoea has been reported by Fourman (1948), Brien, Turner, Watson, and Geddes (1952), Gardner and Perez Santiago (1956), Benson, Culver, Ragland, Jones, Drummey, and Bougas (1957), Finlay and Wightman (1958), and Butterworth, Perez Santiago, Martinez-de Jesus, and Santini (1959). The purpose of this paper is to assess this test as a routine diagnostic measure in the investigation of disorders of the small intestine.…”

The Automatic Determination of Xylose

“…Bell, J. L. and Baron, D. N. (1960) Measurement of the urinary excretion of D( +) have been described for the measurement of Xylose following the oral ingestion of a known Xylose in urine. The method of Crowley (1961) dose has been shown to be a reliable means of suffers from lack of specificity and has been assessing intestinal absorption (Fourman, 1948; criticised by Lanzkowsky, Klassen and Wilson Benson, Culver, Ragland, Jones, Drummey and (1963) on this account, who proposed an Bougas, 1957; Christiansen, Kirsner and Ablaza, alternative method based on the manual method 1959). With increasing use of the Xylose toler-of Roe and Rice (1948).…”