Recent trends in burn epidemiology worldwide: a systematic review.

Smolle, Christian

doi:10.26226/morressier.594bbebed462b8028d893d2d

Cited by 61 publications

(72 citation statements)

References 43 publications

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“…But this data is true only for low and low middle income country for high income country it is the males who are more affected. A systematic review done by Smolle et al (2017) 22 which included the data mostly of high income countries found the mean male:female ratio of all studies together was 1.92:1. The TBSA(Total Body Surface Area) burn group were mostly between 0 and 20%.This result Acinetobacter is increasingly recognized as a significant healthcareassociated, opportunistic and multidrug-resistant pathogen.…”

Section: Resultsmentioning

confidence: 99%

Bacteriological Profile of Burn Patients and Antimicrobial Susceptibility Pattern of their Wound Isolates at Nepal Cleft and Burn Center

Lamichhane

Nakarmi

Dahal

et al. 2019

J Coll Med Sci-Nepal

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Background: Burn infections are the major causes of morbidity and mortality in burn patients. The infectious agent could be both Gram positive and Gram negative bacteria. The aim of this research was to study the bacteriological profile of burn patients and anti-microbial susceptibility pattern of their wound isolates. Methods: This cross-sectional study was conducted in Kirtipur Hospital, Nepal from January 1st to March 31st 2019. A total of 109 burn patients were included and their wound swabs were collected at the time of admission. All isolates were identified by standardized microbiological procedures. Anti-microbial susceptibility tests were performed by Kirby Bauer disc diffusion method. Results: Of 109 burn wound samples, 56 (59%) yielded culture growth and the Gram negative isolates were more common than Gram positives (77% vs. 23%). The most common organism isolated was Klebsiella spp. (25%) followed by Acinetobacter spp. (21%) and Staphylococcus aureus (18%). Most burn wound isolates were of resistant strain. Particularly, highly resistant strain of Acinetobacter spp. were isolated, most of which were sensitive to Tigecycline, Polymyxin B and Colistin only. Conclusion : Gram negative isolates were common in burn wound isolates and the antibiotic susceptibility pattern was different for different organisms. The use of antimicrobials should be judicious to further not escalate the problem of antimicrobial resistance in the healthcare settings.

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Section: Resultsmentioning

confidence: 99%

Bacteriological Profile of Burn Patients and Antimicrobial Susceptibility Pattern of their Wound Isolates at Nepal Cleft and Burn Center

Lamichhane

Nakarmi

Dahal

et al. 2019

J Coll Med Sci-Nepal

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“…Sebuah studi serupa tentang perkembangan manajemen luka bakar telah dilakukan, tetapi hanya mengevaluasi populasi Eropa. 1,2 Manajemen nyeri untuk luka bakar merupakan bagian yang tidak terpisahkan dari manajemen luka bakar yang berhubungan dengan proses penyembuhan luka bakar itu sendiri. Penelitian manajemen nyeri pernah dilakukan di RSUP Dr. Hasan Sadikin tahun 2017, menggambarkan efektivitas pemberian analgetik pada nyeri akut selama tahun 2017 didapatkan angka sebesar 70,3%.…”

Section: Pendahuluanunclassified

Evaluasi Kepatuhan Pelaksanaan Standar Prosedur Operasional Manajemen Nyeri pada Pasien Luka Bakar di RSUP Dr. Hasan Sadikin Bandung

Yudhanarko¹,

Suwarman²,

Aditya³

2019

jap

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Nyeri didefinisikan sebagai pengalaman sensorik dan emosional yang tidak menyenangkan terkait dengan kerusakan jaringan aktual atau potensial. Manajemen nyeri pada luka bakar merupakan bagian yang tidak terpisahkan dari terapi luka bakar. Nyeri pada luka bakar merupakan nyeri akut, penanganan yang tidak baik akan menyebabkan komplikasi, salah satunya nyeri kronik. Rumah Sakit Umum Pusat (RSUP) Dr. Hasan Sadikin Bandung telah membuat Standar Prosedur Operasional (SPO) manajemen nyeri yang berguna untuk meningkatkan kepatuhan dalam pelaksanaan manajemen nyeri. Penelitian ini bertujuan mengevaluasi kesesuaian teknik pengkajian, tindak lanjut dan evaluasi ulang nyeri pada pasien luka bakar dengan SPO manajemen nyeri. Penelitian menggunakan metode deskriptif observasional retrospektif terhadap 99 rekam medis pasien luka bakar yang memenuhi kriteria inklusi di RSUP Dr. Hasan Sadikin Bandung pada tahun 2018. Hasil penelitian didapatkankan bahwa pengkajian nyeri yang dilakukan sesuai dengan SPO menggunakan numeric rating scale atau Wong Baker faces pain scale ditemukan pada 99 pasien (100%). Tindak lanjut hasil pengkajian nyeri luka bakar yang dilakukan sesuai dengan SPO sebanyak 71 pasien (72%). Evaluasi ulang setelah tindak lanjut pengkajian nyeri yang sesuai SPO pada 93 pasien (94%). Simpulan, pengkajian nyeri di RSUP Dr. Hasan Sadikin Bandung sudah sesuai dengan SPO manajemen nyeri, namun tindak lanjut dan evaluasi ulang pada nyeri luka bakar belum sesuai dengan SPO manajemen nyeri.Evaluation of Compliance to Standard Operating Procedures for Pain Management in Patients with Burns in Dr. Hasan Sadikin General Hospital BandungPain is defined as an unpleasant sensory and emotional experience related to actual or potential tissue damage. Pain management for burns is an integral part of burn therapy. Pain in burns is an acute pain and poor management will lead to health complications including chronic pain. Dr. Hasan Sadikin General Hospital Bandung has made a standard operating procedure (SOP) for pain management to improve compliance to pain management standard. This study aimed to evaluate the compliance to the standards in assessment techniques, follow-up, and re-evaluation of pain in patients with burn according to the applicable pain management SOP. This was a retrospective descriptive observational study on 99 medical records of burn patients who met the inclusion criteria in Dr. Hasan Sadikin General Hospital Bandung in 2018. The results of the study revealed that the pain assessment for these patient was carried out according to the SOP which refers to the use of a numeric rating scale or Wong Baker face pain scale in 99 patients (100%). In the follow-up, 71 were performed according to the SOP (72%) while the re-evaluation was performed in compliance with the SOP in 93 patients (94%). In conclusion, pain assessment in Dr. Hasan Sadikin General Hospital Bandung is performed in accordance with SOP on pain management but not all patients receive follow-up and re-evaluation of burn pain in accordance with the SOP on pain management.

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“…Severe and large skin burns cause structural and functional pathological changes in all organs and systems of burned persons, which initiates the development of burn disease [14], a disease that has become increasingly widespread in recent years [9,26].…”

Section: Introductionmentioning

confidence: 99%

Comparative analysis of the effects of various detoxification solutions on the structure of the kidneys in experimental burn disease in rats

et al. 2019

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The use of existing infusion solutions, as well as the development, scientific substantiation and implementation of the latest nephroprotective detoxification solutions, remain an urgent problem for combustiologists. The aim of this work is to compare the effects of various detoxification solutions (0.9 % NaCl solution and complex colloid-hyperosmolar solutions – lactoprotein with sorbitol and the newly developed HAES-LX-5 % solution) on the kidney structure in experimental burn disease in rats. The experimental rats were divided into seven groups (fifteen animals each): the first group was intact rats; the second, third and fourth groups were rats without reproduction of experimental burn disease, which had a separate intravenous infusion of 0.9 % NaCl solution, lactoprotein with sorbitol and HAES-LX-5 % at a dose of 10 ml/kg; the fifth, sixth and seventh groups were rats with experimental burn disease (by causing burn injury of the skin with an area of 21-23 % of the body surface), which under the same scheme had an intravenous infusion of the investigated solutions. All studies and the removal of rats from the experiment were performed under deep thiopental intraperitoneal anesthesia. Histological preparations of the renal cortex of the rat were stained with hematoxylin-eosin and examined on an Olympus BX51 microscope. Using ultramicrotome LKB-3 (Sweden) obtained semi-thin sections which were stained with toluidine blue and methylene blue – Azur II; and ultrathin sections were counterstained with uranyl acetate and lead citrate according to Reynolds and examined using a PEM-125K electron microscope. Morphometric measurements (estimation of the area of the vascular glomeruli, the area of the urinary lumen of the capsule of the renal corpuscles; the area of the renal tubules of the nephrons and the area of their lumens, the area of the renal corpuscles, the area of cytoplasm and nuclei of epithelial cells of tubules, and also their nuclear-cytoplasmic ratio) was carried out using the VideoTest-5.0, KAARA Image Base and Microsoft Excel on a personal computer. Statistical analysis of the obtained quantitative indicators was performed using the ІВМ SPSS v. 22.0. for Windows. Functionally different cells of nephrons have been found to die by necrosis, apoptosis and anoikis when infused with detoxification solutions during the development of burn disease; in epithelial cells of nephron tubules, mitophagy and mitoptosis occur. Mitoptosis in epithelial cells of rat tubules of nephrons with experimental burn skin injury is carried out in two ways related to: 1) destruction of the outer mitochondrial membrane; 2) preservation of the outer mitochondrial membrane and involvement of autophagic (mitophagic) mechanisms to release the cell from degraded mitochondrial material. In the first case, the mitochondria first condense, after which its matrix swells and the fragmentation of the cristae occurs due to the destruction of the junction of the cristae. Finally, the outer mitochondrial membrane breaks and the remnants of the cristae (in the form of vesicles) go into the cytoplasm. In the second case, the mitochondria condense, vesicular fragmentation of the cristae occurs, but the rupture of the outer mitochondrial membrane does not occur and the mitochondria are absorbed by the autophagosome (or transformed into the autophagosome). Next is the merger of autophagosomes with lysosomes and the formation of autophagolysosomes, which, under the conditions of effective digestion of the contents, are transformed into vacuoles. The latter are emptied by exocytosis and ensure the release of cells from degraded material. Only lactoprotein with sorbitol has a membrane-plastic effect on the strengthening (enhancement of structuring) of the mitochondrial membrane in part of the mitochondria of epithelial cells of nephron tubules, which is ultrastructurally manifested by an increase in the electron density and thickness of all components of the mitochondria. The maximum membrane effect of lactoprotein with sorbitol against mitochondria manifests itself fourteen days after the experimental burn skin injury and gradually (after twenty-one and thirty days) disappears, which is correlated with an improvement in the overall clinical condition and an improvement in the structural changes in the kidney of animals with burn disease. There is every reason to believe that increased structuration of mitochondria is a preventer of the spread of mitoptosis and mitophagy, the excess of which can lead to cell death.

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Recent trends in burn epidemiology worldwide: a systematic review.

Cited by 61 publications

References 43 publications

Bacteriological Profile of Burn Patients and Antimicrobial Susceptibility Pattern of their Wound Isolates at Nepal Cleft and Burn Center

Bacteriological Profile of Burn Patients and Antimicrobial Susceptibility Pattern of their Wound Isolates at Nepal Cleft and Burn Center

Evaluasi Kepatuhan Pelaksanaan Standar Prosedur Operasional Manajemen Nyeri pada Pasien Luka Bakar di RSUP Dr. Hasan Sadikin Bandung

Comparative analysis of the effects of various detoxification solutions on the structure of the kidneys in experimental burn disease in rats

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