Recent Trends in Photocatalytic Enantioselective Reactions

Verma, Renu; Jindal, P. Jindal P.; Prasad, Jagdish; Kothari, S. L.; Lamba, Narendra Pal; Dandia, Anshu; Khangarot, Rama Kanwar; Chauhan, M. S.

doi:10.1007/s41061-022-00402-9

Cited by 9 publications

(4 citation statements)

References 85 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…With the development of photocatalytic synthesis and electrosynthesis, new ways have become available for the synthesis of various compounds with novel and complex structures. The photocatalyst (PC) itself does not accelerate the reaction; instead, during excitation, the reaction binds to the substrate and produces an intermediate [8] . Visible light-driven photocatalytic redox plays an important role in the generation of active intermediates.…”

Section: Figure 1 Common Nhc Ligand Skeletonmentioning

confidence: 99%

“…The photocatalyst (PC) itself does not accelerate the reaction; instead, during excitation, the PC binds to the substrate and produces an intermediate. 8 Visible-light-driven photocatalytic redox plays an important role in the generation of active intermediates. Electrochemistry 9 is an important technique in organic synthesis reactions; with the electron as a cheap, intrinsically nonpolluting, and easily dosable redox reagent, electrochemistry can be considered a ‘green’ way to carry out redox reactions.…”

Section: Introductionmentioning

confidence: 99%

“…The photocatalyst (PC) itself does not accelerate the reaction; instead, during excitation, the PC binds to the substrate and produces an intermediate. 8 Visible-light-driv-…”

mentioning

confidence: 99%

See 2 more Smart Citations

NHC-Mediated Photochemical/Electrochemical Synthesis of Carbonyl Compounds

Tang,

Yu,

Pan

et al. 2024

Synthesis

View full text Add to dashboard Cite

Great progress has been made in the photochemical/electrochemical reactions of carbonyl compounds catalyzed by N-heterocyclic carbene (NHC), allowing for many incredible reactions. The form of active intermediates hugely varies in different reactions. Under light or electricity, different active intermediates can be generated during NHC-catalyzed reactions depending on their interaction with different substrates and the reaction conditions. Intermediates can be converted into α,β-unsaturated acylazolium, Breslow intermediate, homoenolate, and acylazolium and subsequently undergo single- or double-electron conversions. This study reviews the different active intermediates formed by NHC in photochemical/electrochemical catalysis.

show abstract

Section: Figure 1 Common Nhc Ligand Skeletonmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

NHC-Mediated Photochemical/Electrochemical Synthesis of Carbonyl Compounds

Tang,

Yu,

Pan

et al. 2024

Synthesis

View full text Add to dashboard Cite

show abstract

“…From a synthetic point of view, using biocatalysts is most beneficial when outstanding stereo-and regioselectivity are required. [95][96] Asymmetric organocatalysis and metal-organocatalysis involved in photoreactions, [97][98] either linked to an enzyme (Figure 1c, PE) or in a chemoenzymatic cascade (Figure 1d, EPC), may here stimulate the creation of further hybrid catalysts, as exemplified by the incorporation of a photosensitizer as a non-natural amino acid in a protein. [18] Following such examples, chiral as well as achiral organo-and metalorganocatalysts can be linked to protein backbones generating novel promising catalysts for asymmetric syntheses.…”

Section: Outlook Of Using Light In Enzymatic Systemsmentioning

confidence: 99%

Exciting Enzymes: Current State and Future Perspective of Photobiocatalysis

et al. 2023

View full text Add to dashboard Cite

The recent increase of interest in photocatalysis spread to biocatalysis and triggered a rush for the development of lightdependent enzyme-mediated or enzyme-coupled processes. After several years of intense research on photobiocatalysis, it is time to evaluate the state of the field in a structured manner. In this Perspective, we suggest to group photobiocatalysis into distinct disciplines and provide principal guidelines and standards for the reporting of photobiocatalytic research results as well as advice on performing photobiocatalytic reactions. Over-all, we assess that the field contributes to the diversity of biocatalytic reactions while offering the selectivity of enzymes to photocatalysis. We foresee that the ongoing excitement for light-dependent enzymatic processes will lead to the discovery of novel photobiocatalytic mechanisms to complement biocatalysis with new bond-forming reactions and will provide additional innovative strategies to utilize light as a possible benign energy source.

show abstract

Visible Light‐Induced Enantioselective Radical Reactions Catalyzed by Redox‐Active Chiral Lewis Acids

Cao,

Hong

2024

ChemCatChem

View full text Add to dashboard Cite

This Concept outlines cutting‐edge progress in catalytic and enantioselective radical reactions facilitated by redox‐active chiral Lewis acids upon visible light excitation. These catalytic systems exploit the high reactivity of radical species to enable efficient stereocontrolled radical recombination. We delve into the design, underlying mechanisms, and practical applications of these catalysts, aiming for precise stereocontrolled bond formation. The synergistic blend of chirality and reactivity has brought a new level of precision to enantioselective radical additions, reshaping the approach to asymmetric synthesis. This Concept focuses on the recent progress and effective application of redox‐active chiral Lewis acids, including Rh, Ir, Ga and Ni, in catalyzing enantioselective radical reactions, which offers a comprehensive perspective on modern methods and projecting future directions in enantioselective radical chemistry.

show abstract

Recent Trends in Photocatalytic Enantioselective Reactions

Cited by 9 publications

References 85 publications

NHC-Mediated Photochemical/Electrochemical Synthesis of Carbonyl Compounds

NHC-Mediated Photochemical/Electrochemical Synthesis of Carbonyl Compounds

Exciting Enzymes: Current State and Future Perspective of Photobiocatalysis

Visible Light‐Induced Enantioselective Radical Reactions Catalyzed by Redox‐Active Chiral Lewis Acids

Contact Info

Product

Resources

About