Recombinant azurin-CdSe/ZnS hybrid structures for nanoscale resistive random access memory device

Azurin/CdSe-ZnS-Based Bio-Nano Hybrid Structure for Nanoscale Resistive Memory Device

“…The device can be programmed for 50 cycles with an ON/OFF ratio of around 1000. Thus, the developed device shows high stability and shows a repeatable hysteresis curve, and the performance of the device is better than the recombinant azurin/CdSe-ZnS device [ 20 ], which required a voltage greater than 2.0 V to switch the device ON. Furthermore, the performance of the device can be easily fine-tuned by incorporating various types of CdSe-ZnS nanoparticles that demonstrate a size-dependent carrier relaxation process [ 7 ].…”

“…The conjugation of biomolecules with CdSe-ZnS nanoparticles has been achieved by covalent bond formation via different linker molecules [ 18 ] and with the help of electrostatic interaction in self-assembled cases [ 19 ]. Recently, CdSe-ZnS quantum dots coupled with bio/organic molecules based structures have shown electrical bistability with good charge retention characteristics, during current-voltage ( I-V ) sweep measurements for future memory applications [ 20 ]. Generally, in semiconductor nanoparticles, electrical bistability arises due to the charge confinement [ 21 ]; however, in bio-nano hybrid molecules, the conformational change or the electro-reduction of molecules plays a key role in changing the conductivity of the molecules [ 22 ], which has led to the development of advanced electronic devices with repeatable conductance switching applications.…”

“…Thus, formation of bio-hybrid nanostructures by fine-tuning the surface properties results in excellent electronic and optical properties for an enormous range of applications such as sensing, imaging, delivery, catalysis and memory devices. Hence, hybrid structures containing inorganic nanoparticles are currently emerging as excellent candidates for potential applications in next-generation nonvolatile memory devices [ 20 , 23 ].…”

“…The use of azurin in direct communication with the electrode provides the basis for electron transport for memory applications [ 24 , 25 ]. Recently, we proposed a nanoscale resistive random access memory device based on recombinant azurin and CdSe-ZnS particles [ 20 ]; however, there are drawbacks to making this structure, such as the long time and complicated steps required to generate the hybrid structures using recombinant DNA technology. Furthermore, complex design skills were required to produce recombinant engineered protein at high yield in order to develop these bio-nano hybrids.…”

Nanobiohybrid Material‐Based Bioelectronic Devices

“…Nanomaterials that have been used to develop effective bioelectronic computing systems using protein‐based biomolecules include carbon‐based materials, including CNTs and graphene, metal nanomaterials, and other novel materials that have been hybridized with biomolecules. [ 102,103 ]…”