Reconstruction of refractive-index distribution in off-axis digital holography optical diffraction tomographic system

Kozacki, Tomasz; Krajewski, Rafal; Kujawińska, Małgorzata

doi:10.1364/oe.17.013758

Cited by 68 publications

(27 citation statements)

References 18 publications

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“…Using a diffraction tomography reconstruction algorithm, 3-D RI maps of a sample are obtained from multiple 2-D holograms measured at various angles of illumination, or rotations of a sample. ODT has been employed for the inspection of optical elements such as optical fibers and waveguides [9,10] as well as for the study of pathophysiology of biological cells [11][12][13][14][15][16].Here, we present measurements of 3-D RI distribution of plastic lenses using ODT. Using Mach-Zehnder interferometry, multiple 2-D optical fields of a plastic lens were measured at various orientations, from which 3-D RI distribution of the lens was reconstructed.…”

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confidence: 99%

Large-scale optical diffraction tomography for inspection of optical plastic lenses

Yoon

Park

2016

Opt. Lett.

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Herein is presented an optical diffraction tomography (ODT) technique for measuring 3-D refractive index (RI) maps of optical plastic lenses. A Mach-Zehnder interferometer was used to measure multiple complex optical fields of a plastic lens immersed in RI-matching oil at various rotational orientations. From this, ODT was used to reconstruct a 3-D RI distribution of the plastic lens with unprecedented RI sensitivity (Δn=4.21×10(-5) and high resolution (12.8 μm). As a demonstration, 3-D RI distributions of a 2 mm-diameter borosilicate sphere and a 5 mm-diameter plastic lens were reconstructed. Defects in the lens, generated by pulsed laser ablation, were also detected using the present method.

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confidence: 99%

Large-scale optical diffraction tomography for inspection of optical plastic lenses

Yoon

Park

2016

Opt. Lett.

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“…The technique is also demonstrated for tomographic profiles of microfiber [200,201]. Instead of full rotation, the illumination angle is scanned over a finite range in [202,203].…”

Section: Holographic Tomographymentioning

confidence: 99%

Principles and techniques of digital holographic microscopy

2010

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Abstract. Digital holography is an emerging field of new paradigm in general imaging applications. We present a review of a subset of the research and development activities in digital holography, with emphasis on microscopy techniques and applications. First, the basic results from the general theory of holography, based on the scalar diffraction theory, are summarized, and a general description of the digital holographic microscopy process is given, including quantitative phase microscopy. Several numerical diffraction methods are described and compared, and a number of representative configurations used in digital holography are described, including off-axis Fresnel, Fourier, image plane, in-line, Gabor, and phase-shifting digital holographies. Then we survey numerical techniques that give rise to unique capabilities of digital holography, including suppression of dc and twin image terms, pixel resolution control, optical phase unwrapping, aberration compensation, and others. A survey is also given of representative application areas, including biomedical microscopy, particle field holography, micrometrology, and holographic tomography, as well as some of the special techniques, such as holography of total internal reflection, optical scanning holography, digital interference holography, and heterodyne holography. The review is intended for students and new researchers interested in developing new techniques and exploring new applications of digital holography. C 2010 Society of Photo-Optical Instrumentation Engineers.

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“…In order to acquire quantitative information of the observed sample without labeling, interferometric phase microscopy (IPM) can be used [13][14][15]. Previous works combined optical tweezers and IPM for cells manipulation [16][17][18][19][20][21], however none of them integrated IPM with array of optical traps created by holography methods for TPM of live cells in suspension.…”

Section: Introductionmentioning

confidence: 99%

Tomographic phase microscopy using optical tweezers

et al. 2015

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We review our technique for tomographic phase microscopy with optical tweezers [1]. This tomographic phase microscopy approach enables full 3-D refractive-index reconstruction. Tomographic phase microscopy measures quantitatively the 3-D distribution of refractive-index in biological cells. We integrated our external interferometric module with holographic optical tweezers for obtaining quantitative phase maps of biological samples from a wide range of angles. The close-tocommon-path, off-axis interferometric system enables a full-rotation tomographic acquisition of a single cell using holographic optical tweezers for trapping and manipulating with a desired array of traps, while acquiring phase information of a single cell from all different angles and maintaining the native surrounding medium. We experimentally demonstrated two reconstruction algorithms: the filtered back-projection method and the Fourier diffraction method for 3-D refractive index imaging of yeast cells.

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Reconstruction of refractive-index distribution in off-axis digital holography optical diffraction tomographic system

Cited by 68 publications

References 18 publications

Large-scale optical diffraction tomography for inspection of optical plastic lenses

Large-scale optical diffraction tomography for inspection of optical plastic lenses

Principles and techniques of digital holographic microscopy

Tomographic phase microscopy using optical tweezers

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