Recording Pattern Visual Evoked Potentials Under Chloral Hydrate Sedation

Kw, Wright; Kj, Eriksen; Tj, Shors; Jp, Ary

doi:10.1001/archopht.1986.01050170108032

Cited by 25 publications

(7 citation statements)

References 20 publications

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“…Previous EEG studies using a few occipital electrodes have reported that visual evoked potentials recorded over occipital cortex were suppressed when a rivalrous stimulus was introduced (10)(11)(12). Studies using orthogonal gratings that were modulated in counterphase (13) or tagged with different flicker frequencies (14) also reported that the amplitude of the visual evoked potential generated by the perceptually dominant stimulus was larger that that of the suppressed stimulus.…”

Section: Discussionmentioning

confidence: 98%

Investigating neural correlates of conscious perception by frequency-tagged neuromagnetic responses

Tononi

Srinivasan

Russell

et al. 1998

Proc. Natl. Acad. Sci. U.S.A.

228

148

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In binocular rivalry, a subject views two incongruent stimuli through each eye but consciously perceives only one stimulus at a time, with a switch in perceptual dominance every few seconds. To investigate the neural correlates of perceptual dominance in humans, seven subjects were recorded with a 148-channel magnetoencephalography array while experiencing binocular rivalry. A red vertical grating f lickering at one frequency was presented to one eye through a red filter and a blue horizontal grating f lickering at a different frequency was presented to the other eye through a blue filter. Steady-state neuromagnetic responses at the two frequencies were used as tags for the two stimuli and analyzed with high-resolution power spectra. It was found that a large number of channels showed peaks at both frequencies, arranged in a horseshoe pattern from posterior to anterior regions, whether or not the subject was consciously perceiving the corresponding stimulus. However, the amount of power at the stimulus frequency was modulated in relation to perceptual dominance, being lower in many channels by 50-85% when the subject was not conscious of that stimulus. Binocular rivalry is a useful experimental paradigm for identifying aspects of neural activity that are correlated with conscious experience (1, 2). If two incongruent visual stimuli are simultaneously presented one through each eye, only one stimulus at a time is consciously perceived, and the two percepts alternate every few seconds. It was thought initially that rivalry might reflect competition between monocular neurons in primary visual cortex or at earlier stages. However, recent psychophysical studies have demonstrated that perceptual rivalry can occur even when both stimuli are presented through the same eye or when they are alternated between the eyes (2). Furthermore, single-unit recordings during binocular rivalry in monkeys indicate that, while the firing of most neurons in primary visual cortex correlates with the stimulus but not with the percept (3), the firing of cortical units in higher visual areas, such as inferior temporal cortex and superior temporal sulcus (4), is highly correlated with the visual percept.Human subjects are the referent of choice for investigating conscious perception (5). However, brain activity associated with rivalry is difficult to study in humans with techniques such as positron emission tomography and functional MRI because of their limited temporal resolution. Unit recordings, on the other hand, while offering high temporal resolution as well as neuronal specificity, are typically performed in overtrained animals and are not practical for providing global coverage of neural responses. At the expense of spatial resolution, magnetoencephalograms (MEGs) and electroencephalograms (EEGs) offer the advantage of high temporal resolution and reflect the synchronous activity of large populations of neurons (6, 7). In this study, we made use of a 148-channel MEG array to compare whole-head, steady-state-evoked responses ...

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Section: Discussionmentioning

confidence: 98%

Investigating neural correlates of conscious perception by frequency-tagged neuromagnetic responses

Tononi

Srinivasan

Russell

et al. 1998

Proc. Natl. Acad. Sci. U.S.A.

228

148

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“…The electrophysiologic measures at our initial assessment most strongly linked to vision outcome are: VEP threshold category, amplitude of the flash VEP and amplitude of the N95 component of the PERG to 4° checks. Peak latencies were not useful to predict visual outcome (although sedation may alter VEP latencies,22 23 peak latencies are not prognostic in alert or in sedated children with ONH5 10). From fundus photographs, the anatomic measures of severity of ONH based on DD:DM ratio and presence of optic disc pallor were independently associated with visual outcome.…”

Section: Discussionmentioning

confidence: 93%

Clinical electrophysiology and visual outcome in optic nerve hypoplasia

McCulloch

Garcia-Filion

Fink

et al. 2009

British Journal of Ophthalmology

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“…Elles peuvent être rendues nécessaires pour l'examen du sujet, jeunes enfants très agités ou encéphalopathes, incapables d'un minimum de coopération. La sédation par hydrate de chloral (Wright et al 1986), (Fox & Wright, 1990) permet l'enregistrement des PEV chez des enfants de moins de 3 ans, sans modification significative des amplitudes ou temps de culmination par rapport à ce que est enregistré chez l'enfant vigile ; ce n'est pas le cas pour des enfants âgés de plus de 3 ans où les PEV sont, le plus souvent, non discernables après cette sédation.…”

Section: Alcool Et Tabacunclassified

V-5 : Les POTENTIELS ÉVOQUÉS VISUELS corticaux (PEV)

Rigaudière¹

2010

Oeil Et Physiologie De La Vision

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Recording Pattern Visual Evoked Potentials Under Chloral Hydrate Sedation

Cited by 25 publications

References 20 publications

Investigating neural correlates of conscious perception by frequency-tagged neuromagnetic responses

Investigating neural correlates of conscious perception by frequency-tagged neuromagnetic responses

Clinical electrophysiology and visual outcome in optic nerve hypoplasia

V-5 : Les POTENTIELS ÉVOQUÉS VISUELS corticaux (PEV)

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