A 78-year-old female presented with a slowly growing mass on the left axillary region. Physical examination showed a painless giant mass 11 × 8.5 cm in diameter, protruding from the left axillary region. Her past medical history included significant overweight, cerebrovascular stroke, goiter, and hypertension. The patient was bedridden for 5 years due to cerebrovascular stroke. She had no history of surgery or trauma to the left axillary region. Physical examination showed an F I G U R E 1 A giant axillary mass with spontaneous rupture 11 × 8.5 cm in diameter, protruding from the left axillary region (A). Gross examination of the excision specimen showed an encapsulated yellow fatty tissue partially opened to the skin surface (B). H&E sections of the overlying skin showed epidermal atrophy, degenerated collagen fibers, numerous dermal dilated vascular structures and mixed inflammatory infiltration (C). H&E sections of the mass revealed mature benign adipose tissue (D)