Recurrent giant mandibular ameloblastoma in young adults

Gravvanis, Andreas; Koumoullis, H.; Anterriotis, Dimitrios; Tsoutsos, Dimosthenis; Katsikeris, Nick

doi:10.1002/hed.24352

Cited by 8 publications

(3 citation statements)

References 42 publications

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“…Although ameloblastoma is one of the most common tumors of the maxillofacial area, a giant ameloblastoma tumor is rare and generally seen in underdeveloped countries and regions [3,4]. Both patients in our report were from rural areas with less education.…”

Section: Discussionmentioning

confidence: 53%

Reconstruction of the Maxillofacial Defect after Extensive Resection of the Giant Ameloblastoma Using Osteocutaneous Fibular Free Flap

Nguyen

et al. 2018

BJSTR

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Extensive resection of a giant ameloblastoma tumor results in a large defect in both bone and skin tissues that poses a major challenge in their reconstruction. AnOsteocutaneous fibular free flap may be suitable for reconstruction of these complex defects. We describe two cases of reconstruction of complex maxillofacial osteocutaneous defects using an osteocutaneous fibular free flap. Postoperatively, the survived free flaps showed good aesthetic results. Hence, an osteocutaneous fibular free flap may be an appropriate choice to reconstruct large and complex multi-component maxillofacial defects.

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Section: Discussionmentioning

confidence: 53%

Reconstruction of the Maxillofacial Defect after Extensive Resection of the Giant Ameloblastoma Using Osteocutaneous Fibular Free Flap

Nguyen

et al. 2018

BJSTR

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“…However, this approach leads to severe maxillofacial deformity and results in compromised stomatognathic function, which causes impaired quality of life and psychological distress. Therefore, oral and maxillofacial surgeons are faced with a dilemma between conservative treatment and radical treatment when dealing with patients with ameloblastoma, especially giant ameloblastoma [6]. Some studies have shown that cystic ameloblastoma decreases in size after marsupialization, and the shrinking of tumor bulk makes subsequent surgical treatment easier and less extensive [7,8].…”

Section: Introductionmentioning

confidence: 99%

Giant Mandibular Ameloblastoma with Rare Hypercalcemia: A Case Report and Literature Review

Shen,

Xu,

Wang

et al. 2023

Medicina

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Ameloblastoma is the most common benign odontogenic tumor with local invasion and high recurrence, which generally occurs in the jaw bones. Hypercalcemia is a common paraneoplastic syndrome that is commonly observed in patients with malignancies but rarely encountered in patients with benign tumors. Thus far, not many cases of ameloblastoma with hypercalcemia have been reported, and the pathogenic mechanism has not been studied in depth. This paper presents a case report of a 26-year-old male diagnosed with giant ameloblastoma of the mandible, accompanied by rare hypercalcemia. Additionally, a review of the relevant literature is conducted. This patient initially underwent marsupialization, yet this treatment was not effective, which indicated that the selection of the appropriate operation is of prime importance for improving the prognosis of patients with ameloblastoma. The tumor not only failed to shrink but gradually increased in size, accompanied by multiple complications including hypercalcemia, renal dysfunction, anemia, and cachexia. Due to the contradiction between the necessity of tumor resection and the patient’s poor systemic condition, we implemented a multi-disciplinary team (MDT) meeting to better evaluate this patient’s condition and design an individualized treatment strategy. The patient subsequently received a variety of interventions to improve the general conditions until he could tolerate surgery, and finally underwent the successful resection of giant ameloblastoma and reconstruction with vascularized fibular flap. No tumor recurrence or distance metastasis was observed during 5 years of follow-up. Additionally, the absence of hypercalcemia recurrence was also noted.

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“…Ameloblastoma is a benign but locally aggressive odontogenic epithelial neoplasm that presents as a slowly growing painless swelling of the jaws and accounts for approximately 1% of all mandibular tumors and cysts (1). Although histologically benign, ameloblastoma can be locally destructive, spreading to the base of the skull, paranasal sinuses, infratemporal fossa, pterygopalatine fossa, parapharyngeal space, therefore causing severe facial deformity and functional impairment (2,3).…”

Section: Introductionmentioning

confidence: 99%

Giant ameloblastoma with intracranial invasion treated with a pure endoscopic approach

Karımzada¹,

Deveci²,

Durmaz³

et al. 2022

GMJ

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Recurrent giant mandibular ameloblastoma in young adults

Abstract: Aggressive resection of the GMA and immediate reconstruction is strongly advised. © 2015 Wiley Periodicals, Inc. Head Neck 38: E1947-E1954, 2016.

Cited by 8 publications

References 42 publications

Reconstruction of the Maxillofacial Defect after Extensive Resection of the Giant Ameloblastoma Using Osteocutaneous Fibular Free Flap

Reconstruction of the Maxillofacial Defect after Extensive Resection of the Giant Ameloblastoma Using Osteocutaneous Fibular Free Flap

Giant Mandibular Ameloblastoma with Rare Hypercalcemia: A Case Report and Literature Review

Giant ameloblastoma with intracranial invasion treated with a pure endoscopic approach

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