2022
DOI: 10.31288/oftalmolzh202244957
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Recurrent ocular toxoplasmosis infection in a patient with a selective deficiency of NK T-cells and cytotoxic СD8+ T-cells associated with a genetic folate cycle deficiency

Abstract: This paper reports a case of recurrent toxoplasmic chorioretinitis in a patient with cellular immunodeficiency. A 37-year-old male presented to an ophthalmologist with complaints of reduced visual acuity and discomfort in his left eye. He had a history of at least two episodes of acute posterior uveitis without identifying the cause of inflammation. An ophthalmoscopic evaluation revealed a scar in the right retina and signs of acute vitritis and chorioretintis surrounding a scar in the left retina. Paired sero… Show more

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“…Non-significant superiority of BF and PFME over the PFME group alone on the quality of life of SUI patients could be explained by the concept of quality of life itself, which is variable and depends on multiple variables ranging from physical, psychological and even social domains, which are multifactorial and not relay of PFM strength, which is the primary outcome from adding BF to PFME, which is not necessary to extend its effect to other aspects of life as patient satisfaction, social interaction and quality of life improvement [59][60][61]. Also, the effect of SUI on the patient's quality of life is variable across patients depending on the severity of the disease, other associated diseases and even other personal expectations from treatment [62][63][64][65][66]. Some patients consider the reduction of the frequency and amount of leakage as a primary goal for a better quality of life, while others need additive assistance to enhance their quality of life.…”
Section: Discussionmentioning
confidence: 99%
“…Non-significant superiority of BF and PFME over the PFME group alone on the quality of life of SUI patients could be explained by the concept of quality of life itself, which is variable and depends on multiple variables ranging from physical, psychological and even social domains, which are multifactorial and not relay of PFM strength, which is the primary outcome from adding BF to PFME, which is not necessary to extend its effect to other aspects of life as patient satisfaction, social interaction and quality of life improvement [59][60][61]. Also, the effect of SUI on the patient's quality of life is variable across patients depending on the severity of the disease, other associated diseases and even other personal expectations from treatment [62][63][64][65][66]. Some patients consider the reduction of the frequency and amount of leakage as a primary goal for a better quality of life, while others need additive assistance to enhance their quality of life.…”
Section: Discussionmentioning
confidence: 99%