Recurrent Pneumonia in an Infant

Abstract

A full-term 2719-g female infant was transferred to a neonatal intensive care unit (NICU) on day 1 of life after developing respiratory distress requiring endotracheal intubation. Gestation was complicated by polyhydramnios and gestational diabetes. In the NICU, choking and desaturation were noted with oral feeding. Videofluoroscopic swallow study demonstrated aspiration with all consistencies. Microlaryngoscopy and bronchoscopy were conducted, and the patient was diagnosed as having a type II laryngeal cleft. At 2 weeks of age, she decompensated secondary to Klebsiella pneumoniae sepsis and was intubated for persistent left lung collapse. At that time, computed tomographic (CT) imaging was performed, revealing the etiology of her respiratory decompensation (Figure 1). Figure 1. Coronal computed tomographic image of the chest with contrast.

Immunopathogenesis of patients with COVID-19: from the perspective of immune system ‘evolution’ and ‘revolution’

“…Pneumonia is the most common infectious disease in the newborns (Ref. 59 ). It is reported that the occurrence of pneumonia is related to the weakened immunity of newborns, such as low levels of IL-2 in neonates with pneumonia, impaired number of CD4 + T and CD8 + T lymphocytes, and decreased levels of IgM and IgG antibodies (Ref.…”